Lim Tae Yoon, Park Samina, Kang Chang Hyun
Department of Anesthesiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Korean J Thorac Cardiovasc Surg. 2019 Aug;52(4):195-204. doi: 10.5090/kjtcs.2019.52.4.195. Epub 2019 Aug 5.
Lobectomy is considered the standard strategy for early-stage non-small cell lung cancer (NSCLC). However, sublobar resection for NSCLC has recently received increased attention. The objective of this study was to compare 5-year survival, recurrence-free survival, postoperative mortality, and postoperative morbidities in patients who received segmentectomy versus those who received lobectomy through a meta-analysis. Sixteen studies were included and the combined hazard ratios or odds ratios were calculated. The results revealed that the 5-year survival rate after segmentectomy was comparable to that of lobectomy for stage IA NSCLC. However, segmentectomy for stage I NSCLC had lower rates of postoperative mortality and morbidities than lobectomy.
肺叶切除术被认为是早期非小细胞肺癌（NSCLC）的标准治疗策略。然而，NSCLC的亚肺叶切除最近受到了更多关注。本研究的目的是通过荟萃分析比较接受肺段切除术的患者与接受肺叶切除术的患者的5年生存率、无复发生存率、术后死亡率和术后并发症。纳入了16项研究并计算了合并风险比或比值比。结果显示，对于IA期NSCLC，肺段切除术后的5年生存率与肺叶切除术相当。然而，I期NSCLC的肺段切除术的术后死亡率和并发症发生率低于肺叶切除术。
