Ana Beristain, de la Torre Fernando
H. Monte Naranco, Oviedo, Asturias Spain.
2ALK-Abelló, S.A., C/Miguel Fleta 19, 28039 Madrid, Spain.
Clin Transl Allergy. 2019 Aug 6;9:39. doi: 10.1186/s13601-019-0276-5. eCollection 2019.
This multicentre, cross-sectional study conducted in Spain assessed the clinical characteristics and quality of life of patients who were aged 14-55 years and had allergic rhinitis and/or asthma, which was due to house dust mite sensitisation, for at least 2 years. Overall, 296 patients were included; 60% had allergic rhinitis (mostly persistent moderate-to-severe) and 40% had rhinitis and asthma (mostly intermittent or mild-to-persistent). Patients with rhinitis had moderately reduced quality of life, which was significantly worse in adults than adolescents. The impact of asthma on quality of life was less pronounced than that of rhinitis. Our findings show that allergic asthma and/or rhinitis due to house dust mites have a moderately negative impact on quality of life, particularly in adults, and that quality of life is significantly influenced by rhinitis.
这项在西班牙开展的多中心横断面研究评估了年龄在14至55岁、因屋尘螨致敏而患有过敏性鼻炎和/或哮喘至少两年的患者的临床特征和生活质量。总体而言，共纳入了296例患者；60%患有过敏性鼻炎（大多为持续性中重度），40%患有鼻炎和哮喘（大多为间歇性或轻度至持续性）。鼻炎患者的生活质量有中度下降，成人患者的生活质量明显比青少年患者更差。哮喘对生活质量的影响不如鼻炎明显。我们的研究结果表明，屋尘螨引起的过敏性哮喘和/或鼻炎对生活质量有中度负面影响，尤其是在成人中，且生活质量受鼻炎的显著影响。
