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1
Effects of dimethyl sulphoxide on the synthesis of plasma proteins in the human hepatoma HepG2. Induction of an acute-phase-like reaction.二甲基亚砜对人肝癌HepG2细胞血浆蛋白合成的影响。诱导急性期样反应。
Biochem J. 1988 Aug 1;253(3):927-30. doi: 10.1042/bj2530927.
2
The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells.急性期诱导剂和二甲基亚砜对人HepG2肝癌细胞中δ-氨基乙酰丙酸合酶活性的影响。
Biochem J. 1989 Apr 15;259(2):605-7. doi: 10.1042/bj2590605.
3
The effect of dimethyl sulfoxide on heme synthesis and the acute phase reaction in human HepG2 hepatoma cells.二甲基亚砜对人HepG2肝癌细胞血红素合成及急性期反应的影响。
Adv Exp Med Biol. 1989;271:103-14. doi: 10.1007/978-1-4613-0623-8_12.
4
Murine cardiotrophin-1 stimulates the acute-phase response in rat hepatocytes and H35 hepatoma cells.
J Interferon Cytokine Res. 1996 Jan;16(1):69-75. doi: 10.1089/jir.1996.16.69.
5
Synthesis and secretion of some plasma proteins by tissue slices of Morris hepatoma 7777 and liver from control and turpentine-injected rats.来自对照大鼠和松节油注射大鼠的正常肝脏组织以及Morris肝癌7777组织切片对某些血浆蛋白的合成与分泌
Folia Histochem Cytochem (Krakow). 1983;21(3-4):211-8.
6
Liver albumin synthesis increases in free ribosomes during the acute-phase reaction.在急性期反应期间，肝脏白蛋白的合成在游离核糖体中增加。
Biochem Biophys Res Commun. 1988 Apr 29;152(2):744-52. doi: 10.1016/s0006-291x(88)80101-3.
7
Differential effects of dimethyl sulfoxide and sodium butyrate on alpha-fetoprotein, albumin, and transferrin production by rat hepatomas in culture.二甲基亚砜和丁酸钠对培养的大鼠肝癌细胞产生甲胎蛋白、白蛋白及转铁蛋白的不同作用
In Vitro. 1981 Apr;17(4):275-83. doi: 10.1007/BF02618138.
8
Enhanced albumin production by malignantly transformed hepatocytes during in vitro exposure to dimethylsulfoxide.体外暴露于二甲基亚砜期间恶性转化的肝细胞白蛋白生成增强。
Biochim Biophys Acta. 1980 Nov 14;610(1):174-80. doi: 10.1016/0005-2787(80)90067-2.
9
Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event.二甲基亚砜对人肝癌细胞系Hep G2血红素合成的诱导作用：一个转录激活事件
Biochem J. 1986 Jul 15;237(2):597-600. doi: 10.1042/bj2370597.
10
[Synthesis of alpha-fetoprotein, albumin and transferrin by long-term cultured cells of murine hepatoma].
Biull Eksp Biol Med. 1979 Jul;88(7):76-8.

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Autism Spectrum Disorder and Fetal Alcohol Spectrum Disorder: A Literature Review.自闭症谱系障碍与胎儿酒精谱系障碍：文献综述
Brain Sci. 2022 Jun 16;12(6):792. doi: 10.3390/brainsci12060792.
2
Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis.鉴定触珠蛋白为系统性血管炎患者血清中的一种血管生成因子。
J Clin Invest. 1993 Mar;91(3):977-85. doi: 10.1172/JCI116319.
3
The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells.急性期诱导剂和二甲基亚砜对人HepG2肝癌细胞中δ-氨基乙酰丙酸合酶活性的影响。
Biochem J. 1989 Apr 15;259(2):605-7. doi: 10.1042/bj2590605.

本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Synthesis and regulation of acute phase plasma proteins in primary cultures of mouse hepatocytes.小鼠肝细胞原代培养物中急性期血浆蛋白的合成与调节
J Cell Biol. 1983 Sep;97(3):866-76. doi: 10.1083/jcb.97.3.866.
3
A Rauscher-virus-induced T-lymphocyte cell line. Induction of differentiation under influence of dimethylsulfoxide and phorbolesters.一种劳舍尔病毒诱导的T淋巴细胞系。在二甲基亚砜和佛波酯影响下的分化诱导。
Int J Cancer. 1983 Oct 15;32(4):501-6. doi: 10.1002/ijc.2910320418.
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Protein accumulation in cultures of hepatic tumor cells exposed to dimethylsulfoxide.暴露于二甲基亚砜的肝癌细胞培养物中的蛋白质积累。
Oncology. 1984;41(5):338-42. doi: 10.1159/000225850.
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Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen.人肝癌细胞系分泌主要血浆蛋白和乙型肝炎表面抗原。
Science. 1980 Jul 25;209(4455):497-9. doi: 10.1126/science.6248960.
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Hepatocyte-stimulating factor: a monocyte-derived acute-phase regulatory protein.肝细胞刺激因子：一种单核细胞衍生的急性期调节蛋白。
Ann N Y Acad Sci. 1983 Jun 27;408:490-502. doi: 10.1111/j.1749-6632.1983.tb23268.x.
7
Human keratinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse.人类角质形成细胞和单核细胞释放的因子可调节人、大鼠和小鼠肝细胞中主要急性期血浆蛋白的合成。
J Biol Chem. 1984 Jun 10;259(11):7331-42.
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Induction of differentiation in Herpetomonas samuelpessoai by dimethylsulfoxide.二甲基亚砜诱导萨氏赫氏鞭毛虫的分化
Acta Trop. 1981 Mar;38(1):29-37.
9
Differentiation-inducing agents decrease cryptic prolactin receptors in cultured rat mammary tumor cells.分化诱导剂可降低培养的大鼠乳腺肿瘤细胞中隐蔽的催乳素受体水平。
Exp Cell Res. 1984 Nov;155(1):17-23. doi: 10.1016/0014-4827(84)90763-8.
10
Induction of microvillar hydrolase activities by cell density and exogenous differentiation inducers in an established kidney epithelial cell line (LLC-PK1).在已建立的肾上皮细胞系（LLC-PK1）中，通过细胞密度和外源性分化诱导剂诱导微绒毛水解酶活性。
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二甲基亚砜对人肝癌HepG2细胞血浆蛋白合成的影响。诱导急性期样反应。

Effects of dimethyl sulphoxide on the synthesis of plasma proteins in the human hepatoma HepG2. Induction of an acute-phase-like reaction.

作者信息

Iwasa F, Galbraith R A, Sassa S

机构信息

Rockefeller University Hospital, New York, NY 10021.

出版信息

Biochem J. 1988 Aug 1;253(3):927-30. doi: 10.1042/bj2530927.

DOI:10.1042/bj2530927
PMID:3140793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1149393/
Abstract

Effects of dimethyl sulphoxide (Me2SO) on the synthesis of plasma proteins by the human hepatoma cell line HepG2 were examined. Me2SO treatment resulted in decreased synthesis of albumin and alpha-fetoprotein, and in increased synthesis of haptoglobin. Plasma-protein profiles induced by Me2SO treatment were very similar to those seen in acute-phase reactions.

摘要

研究了二甲基亚砜（Me2SO）对人肝癌细胞系HepG2合成血浆蛋白的影响。Me2SO处理导致白蛋白和甲胎蛋白的合成减少，而触珠蛋白的合成增加。Me2SO处理诱导的血浆蛋白谱与急性期反应中所见的非常相似。