Shenzhen Early Diagnosis of Gynecological Major Disease Laboratory, Department of Gynecology, Peking University Shenzhen Hospital, Shenzhen, 518035, Guangdong, China.
Shenzhen Technical Research and Development Center on Gynecologic Oncology, Shenzhen, 518035, Guangdong, China.
World J Surg Oncol. 2019 Aug 13;17(1):141. doi: 10.1186/s12957-019-1689-2.
To evaluate the clinical significance of low-frequency electrical stimulation in preventing urinary retention after radical hysterectomy.
A total of 91 women with stage IA2-IB2 cervical cancer, who were treated with radical hysterectomy and lymphadenectomy from January 2009 to December 2012, were enrolled into this study and were randomly divided into two groups: trail group (48 cases) and control group (43 cases). Traditional bladder function training and low-frequency electrical stimulation were conducted in the trail group, while patients in the control group were only treated by traditional bladder training. The general condition, rate of urinary retention, and muscle strength grades of pelvic floor muscle in the perioperative period were compared between these two groups.
The incidence of postoperative urinary retention in the electrical stimulation group was 10.41%, significantly lower than that in the control group (44.18%), and the difference was statistically significant (P < 0.01). The duration of postoperative fever and use of antibiotics were almost the same between these two groups. Eleven days after surgery, the difference in grades of the pelvic floor muscle between these two groups was not statistically significant. However, 14 days after the operation, grades of the pelvic floor muscle were significantly higher in the trail group than in the control group, and the difference was statistically significant (P < 0.01). In addition, although there was no significant difference between the two groups with different parameters (P = 0.782), the incidence of urinary retention was lower in the endorphins analgesia program group than in the neuromuscular repair program group (9.09% < 11.54%).
Low-frequency electrical stimulation is more effective than conventional intervention in preventing urinary retention after radical hysterectomy. It also intensifies the recovery of pelvic muscle strength.
评估低频电刺激预防根治性子宫切除术后尿潴留的临床意义。
本研究共纳入 91 例 2009 年 1 月至 2012 年 12 月接受根治性子宫切除术和淋巴结切除术的 IA2-IB2 期宫颈癌患者，随机分为试验组（48 例）和对照组（43 例）。试验组进行传统膀胱功能训练和低频电刺激，对照组仅进行传统膀胱训练。比较两组患者围手术期一般情况、尿潴留发生率和盆底肌肌力分级。
电刺激组术后尿潴留发生率为 10.41%，明显低于对照组（44.18%），差异有统计学意义（P<0.01）。两组术后发热时间和抗生素使用时间差异无统计学意义。术后 11 天，两组盆底肌肌力分级差异无统计学意义。但术后 14 天，试验组盆底肌肌力分级明显高于对照组，差异有统计学意义（P<0.01）。此外，两组不同参数间差异无统计学意义（P=0.782），但内啡肽镇痛方案组的尿潴留发生率低于神经肌肉修复方案组（9.09%<11.54%）。
低频电刺激预防根治性子宫切除术后尿潴留的效果优于传统干预，同时能增强盆底肌肌力的恢复。
