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针对特发性慢性盆腔疼痛综合征男性患者的综合盆底物理治疗方案:一项前瞻性研究。

Comprehensive pelvic floor physical therapy program for men with idiopathic chronic pelvic pain syndrome: a prospective study.

作者信息

Masterson Thomas A, Masterson John M, Azzinaro Jessica, Manderson Lattoya, Swain Sanjaya, Ramasamy Ranjith

机构信息

Department of Urology, University of Miami, Miami, Florida, USA.

Department of Physical Therapy, University of Miami, Miami, Florida, USA.

出版信息

Transl Androl Urol. 2017 Oct;6(5):910-915. doi: 10.21037/tau.2017.08.17.

Abstract

BACKGROUND

Male chronic pelvic pain syndrome (CPPS) is a heterogeneous constellation of symptoms that causes significant impairment and is often challenging to treat. In this prospective study, we evaluated men with CPPS who underwent comprehensive pelvic floor physical therapy (PFPT) program. We used the previously validated Genitourinary Pain Index (GUPI) to measure outcomes.

METHODS

We included 14 men who underwent physical therapy for idiopathic CPPS from October 2015 to October 2016. Men with clearly identifiable causes of pelvic pain, such as previous surgery, chronic infection, trauma, prostatitis and epididymitis were excluded. Treatment included: (I) manual therapy (internal and external) of pelvic floor and abdominal musculature to facilitate relaxation of muscles; (II) therapeutic exercises to promote range of motion, improve mobility/flexibility and strengthen weak muscles; (III) biofeedback to facilitate strengthening and relaxation of pelvic floor musculature; (IV) neuromodulation for pelvic floor muscle relaxation and pain relief. GUPI questionnaires were collected at initial evaluation and after the 10th visit. Higher scores reflect worse symptoms. Previous validation of the GUPI calculated a reduction of 7 points to robustly predict being a treatment responder (sensitivity 100%, specificity 76%) and a change in 4 points to predict modest response. Data are presented as medians (ranges).

RESULTS

A total of 10 patients completed 10 visits, and the remaining four patients completed between 5 and 9 visits. The median National Institute of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) score at initial evaluation was 30.8 [16-39] and decreased to 22.2 [7-37] at the tenth visit. Five of the 10 patients (50%) in the study had a reduction of greater than 7 points indicating a robust treatment response, and two (20%) had a change of greater than 4 indicating moderate response. Three patients (30%) did not have any meaningful change in NIH-CPSI and the remaining four are in the process of completing 10 sessions. Duration of therapy appears to predict treatment response. Longer duration has better response.

CONCLUSIONS

Male CPPS is difficult to treat and often requires a multimodal approach. Based on the results of our pilot study, pelvic floor rehabilitation may be an effective treatment option for select patients. A larger study with a control group is needed to validate the routine use of pelvic floor rehabilitation in men with CPPS and predict characteristics of men who would respond to therapy.

摘要

背景

男性慢性盆腔疼痛综合征(CPPS)是一组异质性症状,会导致严重功能障碍,且治疗往往具有挑战性。在这项前瞻性研究中,我们评估了接受全面盆底物理治疗(PFPT)方案的CPPS男性患者。我们使用先前验证过的泌尿生殖系统疼痛指数(GUPI)来衡量治疗结果。

方法

我们纳入了2015年10月至2016年10月间因特发性CPPS接受物理治疗的14名男性。排除有明确可识别的盆腔疼痛原因的男性,如既往手术、慢性感染、创伤、前列腺炎和附睾炎。治疗包括:(I)盆底和腹部肌肉组织的手法治疗(内外治疗)以促进肌肉放松;(II)治疗性锻炼以促进活动范围、改善活动能力/灵活性并增强薄弱肌肉;(III)生物反馈以促进盆底肌肉组织的强化和放松;(IV)神经调节以放松盆底肌肉并缓解疼痛。在初始评估时和第10次就诊后收集GUPI问卷。分数越高表明症状越严重。先前对GUPI的验证表明,降低7分可有力预测为治疗反应者(敏感性100%,特异性76%),变化4分可预测为适度反应。数据以中位数(范围)表示。

结果

共有10名患者完成了10次就诊,其余4名患者完成了5至9次就诊。初始评估时,美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)的中位数为30.8[16 - 39],第10次就诊时降至22.2[7 - 37]。研究中的10名患者中有5名(50%)降低超过7分,表明治疗反应良好,2名(20%)变化超过4分,表明有适度反应。3名患者(30%)的NIH-CPSI没有任何有意义的变化,其余4名患者正在完成10次治疗。治疗持续时间似乎可预测治疗反应。持续时间越长,反应越好。

结论

男性CPPS难以治疗,通常需要多模式方法。根据我们的初步研究结果,盆底康复可能是部分患者的有效治疗选择。需要进行一项有对照组的更大规模研究,以验证盆底康复在CPPS男性患者中的常规应用,并预测对治疗有反应的男性患者的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6875/5673826/2e71b4f83ffd/tau-06-05-910-f1.jpg

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