Cao Jing, Li Hui, Song Shengwen, Zhou Xuyan, Shen Xu
Medical Center for Anesthesia and Pain, First Affiliated Hospital of Jiaxing College, Jiaxing, China.
Department of Anesthesiology, First Affiliated Hospital of Medical College of Zhejiang University, Hangzhou, China.
Transl Neurosci. 2019 Jul 12;10:152-156. doi: 10.1515/tnsci-2019-0026. eCollection 2019.
Dexmedetomidine has a dose-dependent sedative and analgesic effect. To further evaluate the wake-up quality of dexmedetomidine in patients undergoing neurosurgery, a meta-analysis of dexmedetomidine in a randomized controlled trial of general anesthesia was performed. Firstly, an experimental algorithm was proposed, and then the data fusion algorithm was used to conduct randomized controlled trials. The clinical efficacy and safety of dexmedetomidine in the acupuncture of neurosurgical patients were evaluated one by one for quality evaluation and data extraction. The effect of different input variables on the depth of anesthesia was studied by using a multi-data fusion approach. The results show that the data fusion algorithm proposed can effectively connect redundant information and complementary information in multiple data, and estimate the real parameters of the measured object. In addition, data fusion brings great convenience to the design of control algorithms and controllers, and provides an effective basis for system simplification. Experiments have shown that dexmedetomidine is effective and safe in the operation of neurosurgical motor function, and the management of the recovery period is safe and effective. Based on the research, it can provide some reference for the awakening of patients undergoing neurosurgery, and promote the progress and development of medicine.
右美托咪定具有剂量依赖性的镇静和镇痛作用。为进一步评估右美托咪定在神经外科手术患者中的苏醒质量，对右美托咪定在全身麻醉随机对照试验中的情况进行了荟萃分析。首先提出了一种实验算法，然后使用数据融合算法进行随机对照试验。对右美托咪定在神经外科手术患者针刺中的临床疗效和安全性逐一进行质量评估和数据提取。采用多数据融合方法研究了不同输入变量对麻醉深度的影响。结果表明，所提出的数据融合算法能够有效连接多个数据中的冗余信息和互补信息，估计被测对象的真实参数。此外，数据融合为控制算法和控制器的设计带来极大便利，为系统简化提供了有效依据。实验表明，右美托咪定在神经外科运动功能手术中有效且安全，恢复期管理安全有效。基于该研究，可为神经外科手术患者的苏醒提供一定参考，推动医学的进步与发展。
