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ABCD 数据库:化学定义抗体的存储库。

The ABCD database: a repository for chemically defined antibodies.

机构信息

Geneva Antibody Facility, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.

Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.

出版信息

Nucleic Acids Res. 2020 Jan 8;48(D1):D261-D264. doi: 10.1093/nar/gkz714.

Abstract

The ABCD (for AntiBodies Chemically Defined) database is a repository of sequenced antibodies, integrating curated information about the antibody and its antigen with cross-links to standardized databases of chemical and protein entities. It is freely available to the academic community, accessible through the ExPASy server (https://web.expasy.org/abcd/). The ABCD database aims at helping to improve reproducibility in academic research by providing a unique, unambiguous identifier associated to each antibody sequence. It also allows to determine rapidly if a sequenced antibody is available for a given antigen.

摘要

ABCD(化学定义抗体)数据库是一个抗体序列库,整合了抗体及其抗原的 curated 信息,并与化学和蛋白质实体的标准化数据库进行了交叉链接。它免费向学术界开放,可以通过 ExPASy 服务器(https://web.expasy.org/abcd/)访问。ABCD 数据库旨在通过为每个抗体序列提供唯一、明确的标识符,帮助提高学术研究的可重复性。它还可以快速确定给定抗原是否有可用的测序抗体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/193d/6943046/766ca4524e69/gkz714fig1.jpg

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