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窄谱中波紫外线光疗用于蕈样肉芽肿溃疡不愈合供皮区可提高移植物摄取:一例报告

NBUVB Phototherapy at the Donor Site Can Enhance the Graft Uptake in the Nonhealing of Ulcers of Mycosis Fungoides: A Case Report.

作者信息

Ahmad Imran, Maurya Rajesh K, Sushama Sushama, Mahmud Ali A

机构信息

Department of Plastic and Reconstructive Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh, Uttar Pradesh, India.

Department of Dermatology, Kailash Hospital, Khurja, Uttar Pradesh, India.

出版信息

J Cutan Aesthet Surg. 2019 Apr-Jun;12(2):128-131. doi: 10.4103/JCAS.JCAS_77_18.

DOI:10.4103/JCAS.JCAS_77_18
PMID:31413482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6676812/
Abstract

Mycosis fungoides is a rare form of non-Hodgkin's lymphoma, which is formed of mature, skin homing, clonal, malignant T lymphocytes. It can sometimes present with skin ulcers that are difficult to heal because of the presence of large number T lymphocytes and antigen-presenting cells. We present a case of nonhealing ulcers in a patient with mycosis fungoides, which was treated by narrow band ultraviolet B targeted phototherapy followed by split-thickness skin grafting. The graft uptake was well and the donor area also healed without any complications.

摘要

蕈样肉芽肿是一种罕见的非霍奇金淋巴瘤,由成熟的、归巢于皮肤的、克隆性恶性T淋巴细胞组成。由于存在大量T淋巴细胞和抗原呈递细胞,它有时会出现难以愈合的皮肤溃疡。我们报告一例蕈样肉芽肿患者的不愈合溃疡病例,该病例采用窄谱中波紫外线靶向光疗,随后进行中厚皮片移植治疗。移植皮片存活良好,供皮区也顺利愈合,无任何并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/5c41a696664a/JCAS-12-128-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/28f4c1db412f/JCAS-12-128-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/42737850b173/JCAS-12-128-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/bdf4b0dfa8cd/JCAS-12-128-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/5c41a696664a/JCAS-12-128-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/28f4c1db412f/JCAS-12-128-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/42737850b173/JCAS-12-128-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/bdf4b0dfa8cd/JCAS-12-128-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1d/6676812/5c41a696664a/JCAS-12-128-g004.jpg

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NBUVB Phototherapy at the Donor Site Can Enhance the Graft Uptake in the Nonhealing of Ulcers of Mycosis Fungoides: A Case Report.窄谱中波紫外线光疗用于蕈样肉芽肿溃疡不愈合供皮区可提高移植物摄取:一例报告
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本文引用的文献

1
Mycosis fungoides and Sézary syndrome: clinical, histopathological and immunohistochemical review and update.蕈样肉芽肿和塞扎里综合征:临床、组织病理学及免疫组化综述与更新
An Bras Dermatol. 2012 Nov-Dec;87(6):817-28; quiz 829-30. doi: 10.1590/s0365-05962012000600001.
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Mycosis fungoides and sezary syndrome: an update.蕈样肉芽肿和塞扎里综合征:最新进展
Curr Oncol Rep. 2006 Sep;8(5):376-86. doi: 10.1007/s11912-006-0061-1.
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Management of mycosis fungoides. Part 1. Diagnosis, staging, and prognosis.蕈样肉芽肿的管理。第1部分。诊断、分期和预后。
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The role of lymphocytes in human dermal wound healing.淋巴细胞在人类皮肤伤口愈合中的作用。
Br J Dermatol. 2000 Jul;143(1):59-65. doi: 10.1046/j.1365-2133.2000.03591.x.
5
Mechanisms of ultraviolet (UV) B and UVA phototherapy.紫外线(UV)B和UVA光疗的作用机制。
J Investig Dermatol Symp Proc. 1999 Sep;4(1):70-2. doi: 10.1038/sj.jidsp.5640185.
6
Mycosis fungoides with mucinosis follicularis in childhood.儿童蕈样肉芽肿伴毛囊黏蛋白沉积症。
Dermatology. 1999;198(3):284-7. doi: 10.1159/000018131.
7
The effects of ultraviolet radiation on the human immune system.紫外线辐射对人体免疫系统的影响。
Br J Dermatol. 1999 Jun;140(6):995-1009. doi: 10.1046/j.1365-2133.1999.02898.x.
8
Biological effects of narrow-band (311 nm TL01) UVB irradiation: a review.窄带(311纳米TL01)紫外线B照射的生物学效应:综述
J Photochem Photobiol B. 1997 Apr;38(2-3):99-106. doi: 10.1016/s1011-1344(96)07454-4.
9
Prolonged skin allograft survival after photodynamic therapy associated with modification of donor skin antigenicity.光动力疗法联合供体皮肤抗原性改变后同种异体皮肤移植存活时间延长。
Transplantation. 1997 Mar 27;63(6):810-7. doi: 10.1097/00007890-199703270-00004.
10
The treatment of ulcers in patients with mycosis fungoides with split-thickness skin grafts.蕈样肉芽肿患者溃疡的中厚皮片移植治疗。
Ann Plast Surg. 1984 Jul;13(1):20-3. doi: 10.1097/00000637-198407000-00004.