舞蹈症与类固醇对一名患有短暂性头痛伴神经功能缺损和脑脊液淋巴细胞增多综合征患者的疗效：病例报告
Chorea and the effectiveness of steroids in a patient with the syndrome of transient headache with neurologic deficits and cerebrospinal fluid lymphocytosis: a case report.
作者信息
Zhao Lu, Wang Ruihao, Fang Hui, Song Bo, Liang Dongyi, Xu Yuming
机构信息
Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Department of Neurology, University of Erlangen-Nuremberg, D-91054 Erlangen, Germany.
出版信息
J Pain Res. 2019 Jul 24;12:2247-2250. doi: 10.2147/JPR.S204869. eCollection 2019.
BACKGROUND
The clinical manifestations of the transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL) syndrome are variable, and involuntary movements have not been reported. The etiology and treatment of the syndrome are not entirely clarified.
CASE
A 25-year-old female presented with recurrent transient headache, involuntary movements (left upper extremity chorea) and paralysis. Lumbar punctures showed intracranial hypertension and cerebrospinal fluid pleocytosis. Symptoms and intracranial hypertension were relieved after administration of steroids.
DISCUSSION/CONCLUSION: Chorea may also present in the HaNDL syndrome. Steroids might relieve the symptoms of the HaNDL syndrome, which indicates the possible treatment strategy for HaNDL and supports the infectious or postinfectious autoimmune etiology hypothesis.
背景
伴有脑脊液淋巴细胞增多的短暂性头痛和神经功能缺损（HaNDL）综合征的临床表现多变，且尚未有不自主运动的相关报道。该综合征的病因和治疗尚未完全明确。
病例
一名25岁女性出现反复发作的短暂性头痛、不自主运动（左上肢舞蹈症）和瘫痪。腰椎穿刺显示颅内高压和脑脊液细胞增多。给予类固醇治疗后，症状和颅内高压得到缓解。
讨论/结论：舞蹈症也可能出现在HaNDL综合征中。类固醇可能缓解HaNDL综合征的症状，这提示了HaNDL可能的治疗策略，并支持感染性或感染后自身免疫病因假说。
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