Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Nutr Cancer. 2020;72(5):778-790. doi: 10.1080/01635581.2019.1651880. Epub 2019 Aug 16.
The Dietary Approaches to Stop Hypertension (DASH) diet has been associated with reduced hypertension and risk of cardiovascular diseases, nevertheless DASH diet is rich in foods that are recommended to be inversely associated with cancer risk. The objective of the present study was to conduct the first meta-analysis of studies investigating the associations between DASH diet and risk of colorectal cancer. Relevant studies were identified in PubMed and Scopus (up to April 2019). Meta-analysis was conducted to calculate the summary relative risk (RR) estimates based on the highest versus the lowest category of DASH scores. Six articles (four prospective cohorts and two case-controls) were eligible. The pooled adjusted RR of Colorectal cancer for the highest DASH score versus the lowest category was 0.81 (95% confidence interval [CI]: 0.75-0.88). Our findings suggest that adherence to the DASH diet was associated with a lower risk of colorectal cancer. These results support the need to promote healthy diet with higher intake of whole grain, vegetables, fruits, and low-fat dairy products and lower intake of salt, sweets and saturated fat to reduce colorectal cancer risk.
得舒饮食（DASH）与降低高血压和心血管疾病风险有关，但 DASH 饮食富含被建议与癌症风险呈负相关的食物。本研究的目的是对研究 DASH 饮食与结直肠癌风险之间关系的研究进行首次荟萃分析。在 PubMed 和 Scopus（截至 2019 年 4 月）中确定了相关研究。进行荟萃分析以计算基于 DASH 评分最高与最低类别计算的汇总相对风险（RR）估计值。有 6 篇文章（4 项前瞻性队列研究和 2 项病例对照研究）符合条件。最高 DASH 评分与最低类别的结直肠癌的汇总调整 RR 为 0.81（95%置信区间[CI]：0.75-0.88）。我们的研究结果表明，坚持 DASH 饮食与结直肠癌风险降低有关。这些结果支持需要促进健康饮食，增加全谷物、蔬菜、水果和低脂乳制品的摄入量，减少盐、糖和饱和脂肪的摄入量，以降低结直肠癌的风险。
