Department of Oral Pathology, School of Dentistry, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of Korea.
Department of Oral and Maxillofacial Radiology, School of Dentistry, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of Korea.
Diagn Pathol. 2019 Aug 17;14(1):92. doi: 10.1186/s13000-019-0867-4.
A primordial odontogenic tumor (POT) is a rare, benign, mixed epithelial and mesenchymal odontogenic tumor that has been included as a new entity in the latest World Health Organization (WHO) classification (2017). POT consists of dental papilla-like myxoid connective tissue covered with a delicate membrane of ameloblastic epithelium. Only 15 cases have been documented worldwide, and here, we report the sixteenth case and the first one of South Korea.
An asymptomatic lesion was discovered as an incidental radiographic finding in a 10-year-old boy. The patient had no complaints about the lesion. Cone-beam computerized tomograms revealed a round cavity with a defined cortical border measuring approximately 5 × 5 × 5 mm in size. The lesion was a POT. The patient was treated with enucleation. The tumor showed no recurrence for one year.
This is the first report of POT in South Korea using the novel diagnosis of POT after it was recognized and defined in the latest WHO classification. This novel diagnosis will be useful for pathologists and clinicians in diagnosing and differentiating this new and rare disease from other odontogenic tumors.
原始性牙源性肿瘤（POT）是一种罕见的良性混合性上皮和间叶性牙源性肿瘤，已被纳入最新的世界卫生组织（WHO）分类（2017 年）中的一个新实体。POT 由牙乳头样黏液性结缔组织组成，表面覆盖有一层薄的成釉细胞瘤样上皮。全世界仅报道了 15 例病例，我们在此报告第 16 例也是韩国的首例病例。
一名 10 岁男孩因偶然发现的影像学表现而发现无症状病变。患者对病变没有任何抱怨。锥形束计算机断层扫描显示一个边界清晰的圆形腔，大小约为 5×5×5mm。病变为 POT。患者接受了肿瘤剜除术治疗。肿瘤在一年后无复发。
这是首例在韩国使用最新的 WHO 分类中识别和定义的 POT 进行诊断的 POT 病例报告。这种新的诊断方法将有助于病理学家和临床医生诊断和鉴别这种新的罕见疾病与其他牙源性肿瘤。
