KU Leuven (University of Leuven), Department of Oral Health Sciences, BIOMAT & UZ Leuven (University Hospitals Leuven), Dentistry, Leuven 3000, Belgium; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
KU Leuven (University of Leuven), Department of Oral Health Sciences, BIOMAT & UZ Leuven (University Hospitals Leuven), Dentistry, Leuven 3000, Belgium; Tanta University, Faculty of Dentistry, Department of Dental Biomaterials, Tanta 31511, Egypt.
Dent Mater. 2019 Oct;35(10):1415-1429. doi: 10.1016/j.dental.2019.07.022. Epub 2019 Aug 14.
Enamel bond durability of three new alternative etchants combined with three representative adhesives was determined.
The 'immediate' and 'aged' micro-tensile bond strength (μTBS) of the 3-step etch&rinse adhesive OptiBond FL ('O-FL', Kerr), 2-step self-etch (SE) adhesive Clearfil SE Bond 2 ('C-SE2', Kuraray Noritake) and universal adhesive Adhese Universal ('ADU', Ivoclar Vivadent) were measured when bonded to enamel following either a proprietary organic acid-containing Enamel Conditioner ('EC', Shofu), a phosphoric-acid monomer-containing Multi Etchant ('ME', Yamakin: 10-methacryloyloxy tetraethylene glycol dihydrogenphosphate or MTEGP), or a metal salt-based ZON etchant ('ZON', Ivoclar Vivadent: ZrO(NO)). All alternative etchants were used in replacement of phosphoric acid, the latter (K-Etchant, Kuraray Noritake) also used with O-FL and ADU, in addition to C-SE2 that was solely used in SE mode (controls). The enamel-etching patterns and de-bonded fracture surfaces were examined by SEM, while the interfaces with enamel were ultra-morphologically characterized by TEM.
No statistically significant difference in immediate and aged μTBS, obtained by combining the three alternative etchants with the three adhesives, was recorded as compared with the respective controls, except for ME combined with O-FL. Upon aging, significant reduction in μTBS was recorded for the ME/C-SE2 and ME/ADU combinations. The percentage of adhesive failures increased with aging. SEM revealed similar etching patterns produced by EC and ZON as by classic phosphoric-acid etching, for which also numerous micro-resin tags at the adhesive-enamel interface were disclosed.
Durable bonding to enamel was generally obtained for all etchant/adhesive combinations with the exception of the ME/O-FL combination.
确定三种新型替代蚀刻剂与三种代表性胶粘剂结合后的牙釉质粘结耐久性。
采用 3 步酸蚀冲洗型胶粘剂 OptiBond FL（O-FL， Kerr）、2 步自酸蚀（SE）胶粘剂 Clearfil SE Bond 2（C-SE2，Kuraray Noritake）和通用胶粘剂 Adhese Universal（ADU，Ivoclar Vivadent），当分别用含专有有机酸的 Enamel Conditioner（EC，Shofu）、含磷酸单体的多蚀刻剂（ME，Yamakin：10-甲丙烯酰氧基四乙二醇二氢磷酸酯或 MTEGP）或基于金属盐的 ZON 蚀刻剂（ZON，Ivoclar Vivadent：ZrO（NO））替代磷酸酸蚀牙釉质后，测量其与牙釉质的“即刻”和“老化”微拉伸粘结强度（μTBS）。所有替代蚀刻剂均替代磷酸使用，后者（K-Etchant，Kuraray Noritake）除了与 O-FL 和 ADU 一起用于 SE 模式外，还与 C-SE2 一起使用，而 C-SE2 仅单独用于 SE 模式（对照）。通过 SEM 检查牙釉质蚀刻图案和分离的断裂表面，通过 TEM 对牙釉质界面进行超微形态学特征分析。
与相应的对照相比，除了 ME 与 O-FL 结合外，用三种替代蚀刻剂与三种胶粘剂组合后，即刻和老化的 μTBS 没有统计学上的显著差异。老化后，ME/C-SE2 和 ME/ADU 组合的 μTBS 显著降低。随着老化，粘接力失效的比例增加。SEM 显示，EC 和 ZON 产生的蚀刻图案与经典磷酸蚀刻相似，在牙釉质与胶粘剂的界面上也发现了许多微树脂标签。
除了 ME/O-FL 组合外，一般来说，所有蚀刻剂/胶粘剂组合都能获得持久的牙釉质粘结。
