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乳制品摄入量与2型糖尿病风险因素:一项叙述性综述。

Dairy intake and type 2 diabetes risk factors: A narrative review.

作者信息

Mitri Joanna, Mohd Yusof Barakatun-Nisak, Maryniuk Melinda, Schrager Cara, Hamdy Osama, Salsberg Veronica

机构信息

Joslin Diabetes Centre, Harvard Medical School, 1 Joslin Place, Boston, MA, 02215, United States.

Department of Nutrition & Dietetics and Research Centre (Non-Communicable Chronic Diseases), Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Malaysia.

出版信息

Diabetes Metab Syndr. 2019 Sep-Oct;13(5):2879-2887. doi: 10.1016/j.dsx.2019.07.064. Epub 2019 Aug 1.

Abstract

AIM

The interest regarding the potential role of dairy products in the prevention of type 2 diabetes (T2D) has emerged. Although results remain mixed, numerous cohort studies have shown that increased dairy consumption is inversely associated with T2D risk. This narrative review evaluates the recent evidence of dairy products intake on T2D risk factors for the prevention of T2D.

MATERIAL AND METHOD

The review is framed within the systematic review and meta-analyses of cohort studies and the individual randomized controlled trials evidence. We searched for existing meta-analyses of cohort studies that addressed the association of dairy intake with incidence of T2D in adults using the MEDLINE (via PubMed) database. For the interventional studies, the literature searched was conducted using MEDLINE (via PubMed) with the following Medical Subjects Heading (MeSH) terms i.e. dairy OR milk OR cheese OR yogurt AND glucose OR diabetes OR insulin resistance OR insulin sensitivity OR pre-diabetes.

RESULTS

Most of the meta-analyses and systematic reviews of the cohort studies point to a reduced risk of T2D with dairy intake of 3 servings per day. This effect was mainly attributed to low-fat dairy, particularly yogurt and cheese. However, there is no evidence in cohort studies that high-fat dairy intake poses any harm.

CONCLUSION

Dairy products, when incorporated into a healthy diet, likely do not have detrimental effects on glucose-related outcomes. The potential impact of dairy consumption on glucose tolerance tests, insulin levels, insulin sensitivity measures, and plasma glucose levels warrant future investigation.

摘要

目的

乳制品在预防2型糖尿病(T2D)中的潜在作用已引发关注。尽管结果仍不一致,但众多队列研究表明,增加乳制品摄入量与T2D风险呈负相关。本叙述性综述评估了近期关于乳制品摄入对预防T2D的T2D风险因素的证据。

材料与方法

本综述以队列研究的系统评价和荟萃分析以及个体随机对照试验证据为框架。我们使用MEDLINE(通过PubMed)数据库搜索了关于成人乳制品摄入量与T2D发病率之间关联的现有队列研究荟萃分析。对于干预性研究,使用MEDLINE(通过PubMed)进行文献检索,检索词为以下医学主题词(MeSH),即乳制品或牛奶或奶酪或酸奶以及葡萄糖或糖尿病或胰岛素抵抗或胰岛素敏感性或糖尿病前期。

结果

大多数队列研究的荟萃分析和系统评价表明,每天摄入3份乳制品可降低T2D风险。这种效果主要归因于低脂乳制品,尤其是酸奶和奶酪。然而,队列研究中没有证据表明摄入高脂乳制品有任何危害。

结论

将乳制品纳入健康饮食时,可能不会对血糖相关结果产生不利影响。乳制品消费对葡萄糖耐量试验、胰岛素水平、胰岛素敏感性测量和血糖水平的潜在影响值得未来研究。

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