Kolluri Harini, Deplewski Dianne
Pediatr Ann. 2019 Aug 1;48(8):e298-e303. doi: 10.3928/19382359-20190724-01.
The importance of vitamin D and its role in several biological processes has been a topic of interest in recent years. Vitamin D is an essential nutrient that is needed for metabolic bone health and for maintaining bone calcium homeostasis. It is primarily synthesized in the skin on exposure to sunlight. Of late, vitamin D deficiency has been associated with conditions such as obesity, poor control of asthma and other autoimmune diseases, which has led to questions about its potential role in causation and management of these conditions. Given the increase in data about this topic, providers may often have questions about whom to screen and what to tell patients. In this article, we address screening guidelines for vitamin D in children and adolescents, management of vitamin D deficiency, and current literature on the role of vitamin D in conditions such as obesity, asthma, and type 1 diabetes mellitus. [Pediatr Ann. 2019;48(8):e298-e303.].
近年来,维生素D的重要性及其在多种生物过程中的作用一直是人们关注的话题。维生素D是一种必需营养素,对代谢性骨骼健康和维持骨骼钙稳态至关重要。它主要在皮肤暴露于阳光时合成。近来,维生素D缺乏与肥胖、哮喘控制不佳及其他自身免疫性疾病等状况相关,这引发了关于其在这些疾病的病因及管理中潜在作用的疑问。鉴于有关该主题的数据不断增加,医疗服务提供者可能经常会有关于筛查对象及告知患者内容的疑问。在本文中,我们阐述了儿童和青少年维生素D的筛查指南、维生素D缺乏的管理,以及关于维生素D在肥胖、哮喘和1型糖尿病等疾病中作用的当前文献。[《儿科年鉴》。2019年;48(8):e298 - e303。]