Division of Cardiology, "Città della Salute e della Scienza di Torino" Hospital, Department of Medical Sciences, University of Turin, 10126 Turin, Italy.
Division of Cardiology, Electrophysiology Lab, Sant'Andrea Hospital, 13100 Vercelli, Italy.
Medicina (Kaunas). 2019 Aug 18;55(8):497. doi: 10.3390/medicina55080497.
Atrial Fibrillation (AF) may be diagnosed due to symptoms, or it may be found as an incidental electrocardiogram (ECG) finding, or by implanted devices recordings in asymptomatic patients. While anticoagulation, according to individual risk profile, has proven definitely beneficial in terms of prognosis, rhythm control strategies only demonstrated consistent benefits in terms of quality of life. In fact, evidence collected by observational data showed significant benefits in terms of mortality, stroke incidence, and prevention of cognitive impairment for patients referred to AF catheter ablation compared to those medically treated, however randomized trials failed to confirm such results. The aims of this review are to summarize current evidence regarding the treatment specifically of subclinical and asymptomatic AF, to discuss potential benefits of rhythm control therapy, and to highlight unclear areas.
心房颤动（AF）可能因症状而被诊断，也可能在无症状患者的常规心电图（ECG）检查或植入设备记录中被偶然发现。虽然根据个体风险状况进行抗凝治疗已被证明在预后方面确实有益，但节律控制策略仅在生活质量方面显示出一致的益处。事实上，观察性数据收集的证据表明，与药物治疗相比，接受 AF 导管消融治疗的患者在死亡率、中风发生率和预防认知障碍方面具有显著获益，但随机试验未能证实这些结果。本综述的目的是总结目前关于亚临床和无症状 AF 治疗的证据，讨论节律控制治疗的潜在获益，并强调尚不清楚的领域。
