Department of Radiology, Medical Imaging Center, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands.
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Chem Commun (Camb). 2019 Sep 16;55(72):10784-10787. doi: 10.1039/c9cc05516a. Epub 2019 Aug 21.
Medical magnetic resonance imaging (MRI) produces high-resolution anatomical images of the human body, but has limited capacity to provide useful molecular information. The light-responsive, liposomal MRI contrast agent described herein could be used to provide an intrinsic theranostic aspect to MRI and enable tracking the distribution and cargo release of drug delivery systems upon light-triggered activation.
医学磁共振成像（MRI）可生成人体高分辨率解剖图像，但提供有用分子信息的能力有限。本文所述的光响应脂质体 MRI 造影剂可用于为 MRI 提供内在的治疗诊断方面，并能够在光触发激活时跟踪药物传递系统的分布和货物释放。
