Santana Natália de Moraes, Mendes Roberta Maria Lins, Silva Nadja Fernandes da, Pinho Cláudia Porto Sabino
Universidade de Pernambuco, Recife, PE, Brazil.
Einstein (Sao Paulo). 2019 Aug 19;17(4):eAO4632. doi: 10.31744/einstein_journal/2019AO4632.
To investigate the potential value of sarcopenia and sarcopenic obesity as prognostic predictors in hospitalized elderly patients with acute myocardial infarction.
A cross-sectional study based on data collected from elderly patients with acute myocardial infarction, admitted to a public hospital located in the Northeastern region of Brazil, from April to July 2015. The diagnosis of sarcopenia was based on muscle mass, muscle strength and physical performance measurements. Cardiovascular risk and prognostic markers, such as troponin and creatine kynase MB isoenzyme values, acute myocardial infarction classification according to ST segment elevation, and thrombolysis in myocardial infarction score were used.
The sample comprised 99 patients with mean age of 71.6 (±7.4) years. Prevalence of sarcopenia and sarcopenic obesity was 64.6% and 35.4%, respectively. Sarcopenia was more prevalent among males (p=0.017) aged >80 years (p=0.008). Thrombolysis in myocardial infarction was the only marker of cardiovascular risk significantly associated with sarcopenia (p=0.002).
Prevalence of sarcopenia was high and associated with thrombolysis in myocardial infarction risk score. Sarcopenic obesity affected approximately one-third of patients and was not associated with any of the prognostic predictors.
探讨肌肉减少症和肌肉减少性肥胖作为住院老年急性心肌梗死患者预后预测指标的潜在价值。
基于2015年4月至7月间入住巴西东北部一家公立医院的老年急性心肌梗死患者收集的数据进行横断面研究。肌肉减少症的诊断基于肌肉量、肌肉力量和身体性能测量。使用了心血管风险和预后标志物，如肌钙蛋白和肌酸激酶MB同工酶值、根据ST段抬高进行的急性心肌梗死分类以及心肌梗死溶栓评分。
样本包括99名平均年龄为71.6（±7.4）岁的患者。肌肉减少症和肌肉减少性肥胖的患病率分别为64.6%和35.4%。肌肉减少症在年龄>80岁的男性中更为普遍（p=0.017）（p=0.008）。心肌梗死溶栓是与肌肉减少症显著相关的唯一心血管风险标志物（p=0.002）。
肌肉减少症的患病率很高，且与心肌梗死溶栓风险评分相关。肌肉减少性肥胖影响了约三分之一的患者，且与任何预后预测指标均无关联。
