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肾衰竭患者胃神经鞘瘤的偶然发现——经微创手术治疗:1例罕见病例报告

Incidental Finding of Gastric Schwannoma in a Renal Failure Patient - Managed by a Minimally Invasive Procedure: Report of a Rare Case.

作者信息

Mujtaba Mohamed A, Al Hillan Alsadiq, Shenouda Daniel, Hossain Mohammad A, Zurkovsky Eugene

机构信息

Department of Internal Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ, USA.

Department of Surgery, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ, USA.

出版信息

Am J Case Rep. 2019 Aug 22;20:1241-1244. doi: 10.12659/AJCR.916487.

Abstract

BACKGROUND Schwannomas are benign tumors originating from any nerve with a Schwann cell sheath. It is an extremely rare tumor, accounting for 0.2% of all gastrointestinal tumors and 4% of all benign tumors of the stomach. Clinical differentiation of gastrointestinal mesenchymal tumors is challenging and confirmatory diagnosis requires biopsy. Surgical resection is the treatment of choice when tumor size is less than 30 mm or when it is located within the muscularis propria. Here, we present a case of a large (>50 mm) gastric Schwannoma that was resected using a new laparoscopic technique suitable for larger tumors. CASE REPORT A 69-year-old woman with past medical history of hypertension, diabetes mellitus, and stroke, and CKD stage 4, presented to the Emergency Department (ED) with persistent nausea, vomiting, and weakness. She was found to have uremia requiring emergent hemodialysis. Eventually, she underwent peritoneal catheter insertion for peritoneal dialysis. A mass on the gastric antrum was found incidentally during the procedure. Biopsy confirmed the diagnosis of gastric Schwannoma. The tumor was removed successfully using a minimally invasive procedure via robotic-assisted laparoscopy. CONCLUSIONS Gastric Schwannoma is a rare submucosal tumor arising from Auerbach's plexus in the muscularis propria. It is usually asymptomatic, but can present with symptoms such as epigastric pain, or upper gastrointestinal bleeding. Tissue biopsy and immunohistochemical staining are the criterion standard for diagnosis. It has no tendency for malignant transformation. Tumors smaller than 30 mm are removed endoscopically, while tumors larger than 30 mm can be removed surgically. In this case, the tumor was removed successfully by minimally invasive robotic-assisted laparoscopy.

摘要

背景

施万细胞瘤是起源于任何有施万细胞鞘的神经的良性肿瘤。它是一种极其罕见的肿瘤,占所有胃肠道肿瘤的0.2%,占所有胃良性肿瘤的4%。胃肠道间质瘤的临床鉴别具有挑战性,确诊需要活检。当肿瘤大小小于30mm或位于固有肌层内时,手术切除是首选治疗方法。在此,我们报告一例使用适合较大肿瘤的新型腹腔镜技术切除的大型(>50mm)胃施万细胞瘤病例。病例报告:一名69岁女性,既往有高血压、糖尿病、中风病史,慢性肾脏病4期,因持续恶心、呕吐和乏力就诊于急诊科。发现她患有需要紧急血液透析的尿毒症。最终,她接受了腹膜透析导管置入术。在此过程中偶然发现胃窦部有一个肿块。活检确诊为胃施万细胞瘤。通过机器人辅助腹腔镜微创方法成功切除了肿瘤。结论:胃施万细胞瘤是一种罕见的起源于固有肌层奥尔巴赫神经丛的黏膜下肿瘤。它通常无症状,但可出现上腹部疼痛或上消化道出血等症状。组织活检和免疫组化染色是诊断的标准。它没有恶变倾向。小于30mm的肿瘤通过内镜切除,而大于30mm的肿瘤可通过手术切除。在本病例中,通过机器人辅助腹腔镜微创成功切除了肿瘤

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76e5/6717397/b7c0f9ab7b18/amjcaserep-20-1241-g001.jpg

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