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内镜超声及内镜切除术在胃神经鞘瘤治疗中的作用

Role of endoscopic ultrasound and endoscopic resection for the treatment of gastric schwannoma.

作者信息

Hu Jinlong, Liu Xiang, Ge Nan, Wang Sheng, Guo Jintao, Wang Guoxin, Sun Siyu

机构信息

Endoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.

出版信息

Medicine (Baltimore). 2017 Jun;96(25):e7175. doi: 10.1097/MD.0000000000007175.

Abstract

Endoscopic ultrasound (EUS) and endoscopic resection play an important role in gastric submucosal tumor. However, there were few articles regarding EUS and endoscopic resection of gastric schwannomas. Our aim was to evaluate the role of EUS and endoscopic resection in treating gastric schwannomas.We retrospectively reviewed 14 patients between March 2012 and April 2016 with gastric schwannomas and who received EUS and endoscopic resection. EUS characteristics, endoscopic resection, tumor features, and follow-up were evaluated in all the patients.Fourteen patients were enrolled in the present study. The patients' ages ranged from 25 to 72 years (mean age, 52.6 years). On EUS, all tumors were originating from muscularis propria and hypoechoic. Ten tumors have the extraluminal growth patterns and 4 tumors have the intraluminal growth patterns. Marginal halos were observed in 7 lesions. No cystic change and calcification were found inside the lesions. Complete endoscopic resection was performed in all the patients with no complications occurring in any patients. No recurrence or metastases was found in all patients during the follow-up period.Gastric schwannoma has some characteristics on EUS, but it is difficult to differentiate gastric schwannoma from gastrointestinal stromal tumor. Endoscopic resection is an effective and safe treatment for gastric schwannoma with an excellent follow-up outcome.

摘要

内镜超声(EUS)和内镜下切除术在胃黏膜下肿瘤中发挥着重要作用。然而,关于EUS及胃神经鞘瘤内镜下切除术的文章较少。我们的目的是评估EUS和内镜下切除术在治疗胃神经鞘瘤中的作用。我们回顾性分析了2012年3月至2016年4月期间14例接受EUS及内镜下切除术的胃神经鞘瘤患者。对所有患者的EUS特征、内镜下切除术、肿瘤特征及随访情况进行了评估。本研究纳入了14例患者。患者年龄在25岁至72岁之间(平均年龄52.6岁)。在EUS检查中,所有肿瘤均起源于固有肌层且呈低回声。10个肿瘤呈腔外生长模式,4个肿瘤呈腔内生长模式。7个病灶可见边缘晕。病灶内未发现囊性变及钙化。所有患者均成功进行了内镜下完整切除,无一例发生并发症。随访期间所有患者均未发现复发或转移。胃神经鞘瘤在EUS上有一些特征,但很难将胃神经鞘瘤与胃肠道间质瘤区分开来。内镜下切除术是治疗胃神经鞘瘤的一种有效且安全的方法,随访结果良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8ef/5484205/73394efce943/medi-96-e7175-g003.jpg

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