Nyland H, Naess A
Acta Neurol Scand. 1978 Nov;58(5):272-9. doi: 10.1111/j.1600-0404.1978.tb02887.x.
Absolute and relative numbers of T lymphocytes in peripheral blood were determined in 19 different groups of patients with neurological diseases, using the E-rosette test. A significantly decreased total number of T lymphocytes was found in the following groups: acute Guillain-Barré syndrome (GBS), active multiple sclerosis (MS), and malignant cerebral tumor. A less pronounced and not significant reduction was observed in patients with amyotrophic lateral sclerosis (ALS). In all other groups of patients normal total numbers of T lymphocytes were found, thus indicating that the decrease in T lymphocyte counts in GBS, MS and malignant cerebral tumors is not due to nonspecific injury of nerve tissue.
使用E-玫瑰花结试验测定了19组不同神经系统疾病患者外周血中T淋巴细胞的绝对数和相对数。在以下几组中发现T淋巴细胞总数显著减少：急性吉兰-巴雷综合征（GBS）、活动期多发性硬化症（MS）和恶性脑肿瘤。在肌萎缩侧索硬化症（ALS）患者中观察到的减少不太明显且无统计学意义。在所有其他患者组中，T淋巴细胞总数正常，因此表明GBS、MS和恶性脑肿瘤中T淋巴细胞计数的减少并非由于神经组织的非特异性损伤。
