Kam-Hansen S, Frydén A, Link H
Acta Neurol Scand. 1978 Aug;58(2):95-103. doi: 10.1111/j.1600-0404.1978.tb02866.x.
B and T cells were defined in cerebrospinal fluid (CSF) and blood of 18 multiple sclerosis (MS), five optic neuritis, and 17 mumps meningitis patients by counting immunoglobulin-bearing lymphocytes for B cells, and the capacity of rosette formation with sheep erythrocytes of T-cell determination. Patients with MS and mumps meningitis had significantly higher T-cell values in CSF compared to blood, while the B cell value was significantly lower in CSF in mumps meningitis only. MS patients also displayed significantly lower B-cell values in blood compared to mumps meningitis patients and blood donors. No significant differences were observed between MS patients in exacerbation and in remission.
通过计数携带免疫球蛋白的淋巴细胞来确定B细胞，并通过T细胞与绵羊红细胞形成玫瑰花结的能力，对18例多发性硬化症（MS）患者、5例视神经炎患者和17例腮腺炎脑膜炎患者的脑脊液（CSF）和血液中的B细胞和T细胞进行了定义。与血液相比，MS患者和腮腺炎脑膜炎患者脑脊液中的T细胞值显著更高，而仅在腮腺炎脑膜炎患者中，脑脊液中的B细胞值显著更低。与腮腺炎脑膜炎患者和献血者相比，MS患者血液中的B细胞值也显著更低。在病情加重和缓解的MS患者之间未观察到显著差异。
