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显性直肠出血:40岁以上患者病因的前瞻性研究

Frank rectal bleeding: a prospective study of causes in patients over the age of 40.

作者信息

Cheung P S, Wong S K, Boey J, Lai C K

机构信息

Department of Surgery, University of Hong Kong, Queen Mary Hospital.

出版信息

Postgrad Med J. 1988 May;64(751):364-8. doi: 10.1136/pgmj.64.751.364.

DOI:10.1136/pgmj.64.751.364
PMID:3143995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2428672/
Abstract

In order to determine the frequency of tumours in patients presenting with frank rectal bleeding, a prospective study was carried out in 337 patients over the age of 40 attending our Proctology Clinic. After making a clinical diagnosis, flexible sigmoidoscopy followed by barium enema was performed. Excluding 7 digitally palpable rectal cancers, there were 30 cancers (9.1%), 34 polyps (10.3%), 7 proctocolitis (2.1%) and 25 diverticula (7.6%) detected, giving a total diagnostic yield of 29.1%. A clinical diagnosis of bleeding sources other than haemorrhoids was made in 80% of the cancers. Flexible sigmoidoscopy detected 93.3% of the cancers and 88.2% of the polyps. Barium enema diagnosed the remaining cancers and polyps but there was a false-positive rate of 3.8%. From our results, we conclude that patients with frank rectal bleeding should be screened routinely for left-colon cancer irrespective of the clinical diagnosis. The flexible sigmoidoscope is a quick and useful tool. However, barium enema should be recommended to individuals with strong clinical suspicion of rectal bleeding other than haemorrhoids.

摘要

为了确定出现明显直肠出血的患者中肿瘤的发生率,我们对337名40岁以上到我院直肠科门诊就诊的患者进行了一项前瞻性研究。做出临床诊断后,先进行乙状结肠镜检查,然后进行钡剂灌肠。排除7例指诊可触及的直肠癌后,共检测到30例癌症(9.1%)、34例息肉(10.3%)、7例直肠结肠炎(2.1%)和25例憩室(7.6%),总诊断率为29.1%。80%的癌症患者做出了除痔疮外其他出血来源的临床诊断。乙状结肠镜检查发现了93.3%的癌症和88.2%的息肉。钡剂灌肠诊断出了其余的癌症和息肉,但假阳性率为3.8%。根据我们的研究结果,我们得出结论,无论临床诊断如何,出现明显直肠出血的患者都应常规筛查左半结肠癌。乙状结肠镜是一种快速且有用的工具。然而,对于临床高度怀疑除痔疮外直肠出血的个体,应推荐进行钡剂灌肠。

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Frank rectal bleeding: a prospective study of causes in patients over the age of 40.显性直肠出血:40岁以上患者病因的前瞻性研究
Postgrad Med J. 1988 May;64(751):364-8. doi: 10.1136/pgmj.64.751.364.
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Screening for colorectal neoplasia in asymptomatic patients using flexible fiberoptic sigmoidoscopy.使用可弯曲纤维乙状结肠镜对无症状患者进行结肠直肠肿瘤筛查。
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Colonoscopic diagnosis and management of rectal bleeding.直肠出血的结肠镜诊断与处理
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Causes of ano-rectal bleeding.肛管直肠出血的原因。
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Fecal occult blood screening for colorectal cancer in a Veterans Administration Hospital.退伍军人管理局医院中结直肠癌的粪便潜血筛查
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