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CTPA、双能CT（DECT）、MRI、V/Q扫描以及SPECT/CT V/Q用于慢性血栓栓塞性肺动脉高压的无创诊断：一项诊断试验准确性的系统评价和网状Meta分析方案

CTPA, DECT, MRI, V/Q Scan, and SPECT/CT V/Q for the noninvasive diagnosis of chronic thromboembolic pulmonary hypertension: A protocol for systemic review and network meta-analysis of diagnostic test accuracy.

作者信息

Xu Shuanglan, Yang Jiao, Zhu Yun, Xu Shuangyan, Liu Jie, Deng Yishu, Wei Li, Yang Mei, Huang Xiaoxian, Cao Bing, Zhang Chunfang, Zhao Fangyun, Liu Xing, Xing Xiqian, Li Zhongming

机构信息

Department of Respiratory Medicine, The Fourth Affiliated Hospital of Kunming Medical University, The Second People's Hospital of Yunnan Province.

First Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University.

出版信息

Medicine (Baltimore). 2019 Aug;98(34):e16787. doi: 10.1097/MD.0000000000016787.

DOI:10.1097/MD.0000000000016787
PMID:31441850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6716738/
Abstract

BACKGROUND

To determine the diagnostic accuracy of techniques with chronic thromboembolic pulmonary hypertension (CTEPH) patients via a protocol for systemic review and network meta-analysis.

METHODS

We will search PubMed, EMBASE, Web of Science, and Google Scholar from inception to October 1, 2018. The reference lists of the retrieved articles are also consulted. Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) will be used to assess the risk of bias in each study. The direct meta-analyses, network meta-analyses, and ranking of competing diagnostic tests will be used by STATA 12.0 and WINBUGS 1.4. Heterogeneity and inconsistency are assessed.

RESULTS

This study is ongoing, will be submitted to a peer-reviewed journal publication once completed.

CONCLUSION

This study will provide a comprehensive evidence summary of diagnostic test accuracy in detecting the CTEPH, and can help patients and clinicians to select appropriate or best diagnostic test.

ETHICS AND COMMUNICATION

No ethical approval and patient consent are required, because it is based on published researches.

PROSPERO REGISTRATION NUMBER

CRD42019121279.

摘要

背景

通过系统评价和网状Meta分析方案，确定慢性血栓栓塞性肺动脉高压（CTEPH）患者相关技术的诊断准确性。

方法

我们将检索自数据库建库至2018年10月1日的PubMed、EMBASE、Web of Science和谷歌学术。同时查阅检索文章的参考文献列表。将使用诊断准确性研究的质量评估2（QUADAS - 2）来评估每项研究中的偏倚风险。将使用STATA 12.0和WINBUGS 1.4进行直接Meta分析、网状Meta分析以及竞争性诊断试验的排序。评估异质性和不一致性。

结果

本研究正在进行中，完成后将提交给同行评审期刊发表。

结论

本研究将提供关于检测CTEPH诊断试验准确性的全面证据总结，并可帮助患者和临床医生选择合适或最佳的诊断试验。

伦理与交流

无需伦理批准和患者同意，因为它基于已发表的研究。

PROSPERO注册号：CRD42019121279。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/d8233dd49d4d/medi-98-e16787-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/aaff0e62d2e3/medi-98-e16787-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/716482ca0369/medi-98-e16787-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/d8233dd49d4d/medi-98-e16787-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/aaff0e62d2e3/medi-98-e16787-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/716482ca0369/medi-98-e16787-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0d/6716738/d8233dd49d4d/medi-98-e16787-g003.jpg

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Dual-energy CT perfusion and angiography in chronic thromboembolic pulmonary hypertension: diagnostic accuracy and concordance with radionuclide scintigraphy.慢性血栓栓塞性肺动脉高压的双能 CT 灌注和血管造影：诊断准确性和与放射性核素闪烁显像的一致性。
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