Hand J W, Walker H, Hornsey S, Field S B
Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Jun;35(6):521-8. doi: 10.1080/09553007914550631.
The effects of both hyperthermia alone and X-rays combined with hyperthermia on mouse testis have been investigated. Testis weight on heating time was observed for temperatures in the range 39.5 to 43.75 degrees C. The relationship between the reaction rate and the reciprocal of absolute temperature indicated that, over the temperature range considered, the activation energy associated with such thermal damage was (646 +/- 45) x 10(3) J mol-1. No evidence was obtained to indicate a change in slope of the Arrhenius plot over this temperature range. Finally, despite the high sensitivity of the testis to heat and X-rays, no thermal enhancement of the weight loss after irradiation was observed when thermal treatments which, if given alone would produce some observable damage, were administered immediately after irradiation.
研究了单纯高温以及X射线与高温联合作用对小鼠睾丸的影响。观察了在39.5至43.75摄氏度范围内不同加热时间下的睾丸重量。反应速率与绝对温度的倒数之间的关系表明，在所考虑的温度范围内，与这种热损伤相关的活化能为(646±45)×10³ J·mol⁻¹。未获得证据表明在此温度范围内阿仑尼乌斯曲线的斜率发生变化。最后，尽管睾丸对热和X射线高度敏感，但当在照射后立即给予单独进行时会产生一些可观察到损伤的热处理时，未观察到照射后体重减轻的热增强现象。
