Maliyekkal Ferhana Firoz, Vijay Sandeep, Attakkil Anoop, Beegum Faseela, Krishnan Ashwathi, Mullath Aswin
Department of Surgical Oncology, Malabar Cancer Centre, Thalassery, Kerala India.
Department of Oncopathology, Malabar Cancer Centre, Thalassery, Kerala India.
J Maxillofac Oral Surg. 2025 Apr;24(2):508-515. doi: 10.1007/s12663-024-02325-y. Epub 2024 Sep 3.
Malignant odontogenic tumors (MOT) are rare malignancies arising either denovo from tooth forming tissues or as malignant transformation of benign odontogenic lesions. Owing to its rarity, there is no available staging or defined evaluation/ treatment guidelines available.
The aim of this study was to report a case series of six MOT cases, to study their clinicoradiological findings at presentation and available treatment modalities.
Data of the patients were collected from medical records including electronic medical records and the pathology reporting section.
Our study showed that all patients who were treated with surgery and adjuvant radiation remained disease free during follow-up. Thus, we recommend that all MOTs should be treated with radical resection followed by adjuvant radiation.
恶性牙源性肿瘤(MOT)是罕见的恶性肿瘤,可原发于牙形成组织,也可由良性牙源性病变恶变而来。由于其罕见性,目前尚无可用的分期或明确的评估/治疗指南。
本研究旨在报告一组6例MOT病例系列,研究其就诊时的临床放射学表现及可用的治疗方式。
从包括电子病历和病理报告科室在内的医疗记录中收集患者数据。
我们的研究表明,所有接受手术及辅助放疗的患者在随访期间均无疾病复发。因此,我们建议所有MOT均应采用根治性切除并辅以辅助放疗进行治疗。