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预测异位妊娠治疗的决策支持系统。

A decision support system for predicting the treatment of ectopic pregnancies.

机构信息

Department of Computer Technology (DTIC), University of Alicante, Carretera San Vicente s/n, 03690 Alicante, Spain.

Service of Gynecology and Obstetrics, "Virgen de la Arrixaca" University Clinical Hospital, Institute for Biomedical Research of Murcia (IMIB-Arrixaca), Ctra. Madrid-Cartagena, s/n, 30120 El Palmar, Murcia, Spain.

出版信息

Int J Med Inform. 2019 Sep;129:198-204. doi: 10.1016/j.ijmedinf.2019.06.002. Epub 2019 Jun 8.

Abstract

BACKGROUND AND OBJECTIVE

Ectopic pregnancy is an important cause of morbidity and mortality worldwide. An early diagnosis, as well as the choice of the most suitable treatment for the patient is crucial to avoid possible complications. According to different factors an ectopic pregnancy must be treated from surgery, using a pharmacological treatment or following a conservative treatment. In this paper, a clinical decision support systems based on artificial intelligence algorithms has been developed to help clinicians to choose the initial treatment to be followed by the patient.

METHODS

A decision support system based on a three stages classifier has been developed. Each stage acts as a filter and allows re-evaluation of the classification made in the previous stage in order to find diagnostic errors. This classifier has been implemented and tested for four different aid algorithms: Multilayer Perceptron, Deep Learning, Support Vector Machine and Naives Bayes.

RESULTS

The results prove that the evaluated algorithms Support Vector Machine and Multilayer Perceptron can be useful to help gynecologists in their decisions about initial treatment, especially with Support Vector Machine that presents accuracy, sensitivity and specificity outcomes about 96.1%, 96% and 98%, respectively.

CONCLUSIONS

According to the results, it is feasible to develop a clinical decision support system using the algorithms that present a higher precision. This system would help gynecologists to take the most accurate decision about the initial treatment, thus avoiding future complications.

摘要

背景与目的

异位妊娠是全球发病率和死亡率的重要原因。早期诊断以及为患者选择最合适的治疗方法至关重要,以避免可能出现的并发症。根据不同的因素,异位妊娠必须通过手术、药物治疗或保守治疗来治疗。在本文中,我们开发了一种基于人工智能算法的临床决策支持系统,以帮助临床医生选择患者应接受的初始治疗。

方法

我们开发了一种基于三阶段分类器的决策支持系统。每个阶段都充当一个过滤器,并允许重新评估前一阶段的分类,以发现诊断错误。我们已经为四种不同的辅助算法实现和测试了这个分类器:多层感知机、深度学习、支持向量机和朴素贝叶斯。

结果

结果证明,评估的算法支持向量机和多层感知机可用于帮助妇科医生做出关于初始治疗的决策,特别是支持向量机,其准确性、敏感性和特异性分别约为 96.1%、96%和 98%。

结论

根据结果,使用具有更高精度的算法开发临床决策支持系统是可行的。该系统将有助于妇科医生对初始治疗做出最准确的决策,从而避免未来的并发症。

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