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Fleroxacin in single dose oral therapy of uncomplicated lower urinary tract infection.

作者信息

Kosmidis J, Gargalianos P, Adamis G, Petropoulou D, Makris D

机构信息

First Department of Medicine, General Hospital, Athens, Greece.

出版信息

J Antimicrob Chemother. 1988 Oct;22 Suppl D:219-21. doi: 10.1093/jac/22.supplement_d.219.

DOI:10.1093/jac/22.supplement_d.219
PMID:3144541
Abstract

A randomized comparative study was performed in twenty women with acute uncomplicated lower urinary tract infection (UTI). They received a single oral dose of either fleroxacin 600 mg or amoxycillin 3 g. Pathogens were Escherichia coli (17), Proteus mirabilis (2) and Staphylococcus aureus (1). A complete clinical and microbiological cure was observed in all patients of both groups. One patient in the fleroxacin group had gastric irritation. A single oral dose of fleroxacin may be suitable for the treatment of lower UTI even when it is due to organisms resistant to amoxycillin and other traditional oral antimicrobials.

摘要

相似文献

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Fleroxacin in single dose oral therapy of uncomplicated lower urinary tract infection.
J Antimicrob Chemother. 1988 Oct;22 Suppl D:219-21. doi: 10.1093/jac/22.supplement_d.219.
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J Antimicrob Chemother. 1988 Oct;22 Suppl D:199-207. doi: 10.1093/jac/22.supplement_d.199.

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Antimicrob Agents Chemother. 1996 Mar;40(3):659-64. doi: 10.1128/AAC.40.3.659.
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Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography.
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