Peng Li, Huang Weirong, Zhang Wenmo, Xu Yuanyuan, Lu Fang, Zhong Ling, Chen Xianchun, Xu Song, Chen Wenjun, Li Min
Department of Military Psychology, School of Psychology, Third Military Medical University, Chongqing, China.
Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Front Psychiatry. 2019 Aug 7;10:537. doi: 10.3389/fpsyt.2019.00537. eCollection 2019.
Currently, fear of cancer recurrence (FCR) is emerging as an important issue for long-term breast cancer survivors and is associated with lower quality of life and functional impairment. Given that there is a dearth of research regarding the FCR of Chinese breast cancer survivors, this study investigated whether the short form of the Fear of Cancer Recurrence Inventory (FCRI) could detect high FCR and explored the level and characteristics of FCR in breast cancer survivors. Two hundred forty patients who had undergone successful breast cancer surgery in China submitted their survey through a website. The participants' demographic and medical data, level of FCR, anxiety, depression, and quality of life were assessed. Two hundred seven patients with ages ranging from 19 to 60 years completed the questionnaires. The mean FCR score of the total sample was 18.39. A cutoff score of 12 or higher on the short form of the FCRI was optimal for the detection of high FCR with a sensitivity of 98.6% and a specificity of 35%, and the PPV (positive predictive values) and NPV (negative predictive values) were 44% and 98%, respectively. The area under the curve of the receiver operating characteristics (ROC) analysis was 83%. A total of 159 breast cancer survivors (76.81%) experienced high FCR levels (FCR score > 12), characterized by lower functional and overall health than survivors with a low FCR ( < 0.01). The short form of the FCRI is capable of detecting high FCR and is therefore able to assist Chinese breast cancer survivors in receiving appropriate care for reducing FCR.
目前,对癌症复发的恐惧(FCR)正成为长期乳腺癌幸存者的一个重要问题,并且与生活质量降低和功能损害相关。鉴于关于中国乳腺癌幸存者FCR的研究匮乏,本研究调查了癌症复发恐惧量表简版(FCRI)是否能够检测出高FCR水平,并探讨了乳腺癌幸存者中FCR的程度和特征。240名在中国成功接受乳腺癌手术的患者通过一个网站提交了调查问卷。评估了参与者的人口统计学和医学数据、FCR水平、焦虑、抑郁及生活质量。207名年龄在19至60岁之间的患者完成了问卷调查。总样本的FCR平均得分为18.39。FCRI简版得分12分及以上对于检测高FCR是最佳的,灵敏度为98.6%,特异度为35%,阳性预测值(PPV)和阴性预测值(NPV)分别为44%和98%。受试者工作特征(ROC)分析的曲线下面积为83%。共有159名乳腺癌幸存者(76.81%)经历了高FCR水平(FCR得分>12),其功能和总体健康状况低于低FCR的幸存者(P<0.01)。FCRI简版能够检测出高FCR,因此能够帮助中国乳腺癌幸存者获得适当的护理以减轻FCR。