Rob Md Mahfuzur, Iwasaki Arihiro, Suzuki Ryota, Suenaga Kiyotake, Kato-Noguchi Hisashi
Department of Applied Biological Science, Faculty of Agriculture, Kagawa University, Miki 761-0795, Japan.
The United Graduate School of Agricultural Sciences, Ehime University, 3-5-7 Tarumi, Matsuyama 790-8566, Japan.
Plants (Basel). 2019 Aug 24;8(9):301. doi: 10.3390/plants8090301.
Plants are sources of diversified allelopathic substances that can be investigated for use in eco-friendly and efficient herbicides. An aqueous methanol extract from the leaves of exhibited strong inhibitory activity against barnyard grass ( (L.) P. Beauv.), foxtail fescue ( (L.) C.C.), alfalfa ( L.), and cress ( L.), and appears to be a promising source of allelopathic substances. Hence, bio-activity guided purification of the extract through a series of column chromatography steps yielded a novel compound assigned as garcienone (()-5-hydroxy-5-((6S, 9S)-6-methyl-9-(prop-13-en-10-yl) tetrahydrofuran-6-yl) pent-3-en-2-one). Garcienone significantly inhibited the growth of cress at a concentration of 10 μM. The concentrations resulting in 50% growth inhibition () of cress roots and shoots were 120.5 and 156.3 μM, respectively. This report is the first to isolate and identify garcienone and to determine its allelopathic potential.
植物是多种化感物质的来源，这些化感物质可用于研究开发环保且高效的除草剂。[植物名称]叶片的甲醇水提取物对稗草（(L.) P. Beauv.）、狐尾羊茅（(L.) C.C.）、苜蓿（L.）和水芹（L.）表现出强烈的抑制活性，似乎是一种很有前景的化感物质来源。因此，通过一系列柱色谱步骤对提取物进行生物活性导向纯化，得到了一种新化合物，命名为藤黄菌素（()-5-羟基-5-((6S, 9S)-6-甲基-9-(丙-13-烯-10-基)四氢呋喃-6-基)戊-3-烯-2-酮）。藤黄菌素在浓度为10 μM时显著抑制水芹的生长。导致水芹根和芽生长抑制50%（）的浓度分别为120.5 μM和156.3 μM。本报告首次分离鉴定了藤黄菌素并确定了其化感潜力。
