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Should Melatonin Be Used as a Sleeping Aid for Elderly People?

出版信息

Can J Hosp Pharm. 2019 Jul-Aug;72(4):327-329. Epub 2018 Aug 31.

PMID:31452545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6699865/
Abstract
摘要

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Should Melatonin Be Used as a Sleeping Aid for Elderly People?褪黑素是否应作为老年人的助眠药物？
Can J Hosp Pharm. 2019 Jul-Aug;72(4):327-329. Epub 2018 Aug 31.
2
Older poor-sleeping women display a smaller evening increase in melatonin secretion and lower values of melatonin and core body temperature than good sleepers.睡眠质量差的老年女性的褪黑素分泌傍晚增幅较小，褪黑素和核心体温值也低于睡眠质量好的女性。
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Bright-light exposure during daytime sleeping affects nocturnal melatonin secretion after simulated night work.白天睡眠期间暴露于强光会影响模拟夜间工作后的夜间褪黑素分泌。
Chronobiol Int. 2018 Feb;35(2):229-239. doi: 10.1080/07420528.2017.1394321. Epub 2017 Nov 16.
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[The role of melatonin receptor and GABAA receptor in the sleeping time prolonged by melatonin in mice].
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The effect of melatonin treatment on postural stability, muscle strength, and quality of life and sleep in postmenopausal women: a randomized controlled trial.褪黑素治疗对绝经后女性姿势稳定性、肌肉力量、生活质量及睡眠的影响：一项随机对照试验
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Life's Essential 8: Optimizing Health in Older Adults.生命的八大基本要素：优化老年人的健康状况。
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Melatonin: A Potential Candidate for the Treatment of Experimental and Clinical Perinatal Asphyxia.褪黑素：治疗实验性和临床围产期窒息的潜在候选药物。
Molecules. 2023 Jan 22;28(3):1105. doi: 10.3390/molecules28031105.
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Pharmacotherapies for sleep disturbances in dementia.痴呆症睡眠障碍的药物治疗
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本文引用的文献

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American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults.美国老年医学学会 2019 年更新的老年人潜在不适当药物使用 AGS Beers 标准®。
J Am Geriatr Soc. 2019 Apr;67(4):674-694. doi: 10.1111/jgs.15767. Epub 2019 Jan 29.
2
Insomnia in Elderly Patients: Recommendations for Pharmacological Management.老年患者失眠：药物治疗建议
Drugs Aging. 2018 Sep;35(9):791-817. doi: 10.1007/s40266-018-0569-8.
3
Sleep disorders in the elderly: a growing challenge.老年人的睡眠障碍：一项日益严峻的挑战。
Psychogeriatrics. 2018 May;18(3):155-165. doi: 10.1111/psyg.12319.
4
Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline.苯二氮䓬类受体激动剂的撤药：基于证据的临床实践指南。
Can Fam Physician. 2018 May;64(5):339-351.
5
Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action.褪黑素与健康：健康结局及生物学作用机制的综合评价
BMC Med. 2018 Feb 5;16(1):18. doi: 10.1186/s12916-017-1000-8.
6
REM Sleep Behavior Disorder: Diagnosis, Clinical Implications, and Future Directions.快速眼动睡眠行为障碍：诊断、临床意义及未来方向。
Mayo Clin Proc. 2017 Nov;92(11):1723-1736. doi: 10.1016/j.mayocp.2017.09.007. Epub 2017 Nov 1.
7
Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders.褪黑素治疗成人原发性睡眠障碍的疗效证据。
Sleep Med Rev. 2017 Aug;34:10-22. doi: 10.1016/j.smrv.2016.06.005. Epub 2016 Jul 20.
8
Over-the-counter medications containing diphenhydramine and doxylamine used by older adults to improve sleep.老年人使用的含有苯海拉明和多西拉敏的非处方药物，用于改善睡眠。
Int J Clin Pharm. 2017 Aug;39(4):808-817. doi: 10.1007/s11096-017-0467-x. Epub 2017 May 2.
9
Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.《成人慢性失眠症药物治疗临床实践指南：美国睡眠医学会临床实践指南》
J Clin Sleep Med. 2017 Feb 15;13(2):307-349. doi: 10.5664/jcsm.6470.
10
Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content.褪黑素天然健康产品及补充剂：含血清素且褪黑素含量存在显著差异。
J Clin Sleep Med. 2017 Feb 15;13(2):275-281. doi: 10.5664/jcsm.6462.