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家族性地中海热与白塞病并存:一例报告

Coexistence of familial Mediterranean fever and Behçet's disease: a case report.

作者信息

Güler Tuba, Garip Yeşim, Dörtbaş Fulya, Karcı Ayşe Aslıhan, Çifçi Nurşad

机构信息

Department of Physical Medicine and Rehabilitation, Derince Training and Research Hospital, Kocaeli, Turkey.

Department of Physical Medicine and Rehabilitation, Başak Medical Center, Ankara, Turkey.

出版信息

Turk J Phys Med Rehabil. 2017 Jun 3;63(2):174-177. doi: 10.5606/tftrd.2017.72681. eCollection 2017 Jun.

Abstract

Behçet's disease (BD) is a chronic, multi-systemic vasculitis, characterized by a triad of recurrent aphthous stomatitis, genital aphthae, and uveitis. It is common in the Eastern Mediterranean, Middle East, and Eastern Asian countries. Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disorder, which is common seen in the Turkish, Armenian, Arabic, and Sephardic Jewish populations. It is characterized by recurrent episodes of fever, peritonitis, pleuritis, arthritis, and erysipelas-like skin lesions. Behçet's disease and FMF have common clinical features and geographic distribution. Herein, we present a 19-year-old female patient with coexistence of FMF and BD in the light of literature data.

摘要

白塞病(BD)是一种慢性多系统血管炎,其特征为复发性口腔溃疡、生殖器溃疡和葡萄膜炎三联征。该病在东地中海、中东和东亚国家较为常见。家族性地中海热(FMF)是一种常染色体隐性自身炎症性疾病,常见于土耳其、亚美尼亚、阿拉伯和西班牙裔犹太人群体。其特征为发热、腹膜炎、胸膜炎、关节炎和丹毒样皮肤损害反复发作。白塞病和家族性地中海热具有共同的临床特征和地理分布。在此,我们根据文献资料介绍一名同时患有家族性地中海热和白塞病的19岁女性患者。

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Coexistence of familial Mediterranean fever and Behçet's disease: a case report.家族性地中海热与白塞病并存:一例报告
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本文引用的文献

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Update on the therapy of Behçet disease.白塞病治疗的最新进展。
Ther Adv Chronic Dis. 2014 May;5(3):112-34. doi: 10.1177/2040622314523062.
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Diagnostic criteria of familial Mediterranean fever.家族性地中海热的诊断标准。
Autoimmun Rev. 2014 Apr-May;13(4-5):388-90. doi: 10.1016/j.autrev.2014.01.045. Epub 2014 Jan 11.
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9
Coexistence of vasculitides with familial Mediterranean fever.血管炎与家族性地中海热并存。
Rheumatol Int. 2011 Oct;31(10):1263-74. doi: 10.1007/s00296-011-1840-z. Epub 2011 Mar 10.

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