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老年患者的带状疱疹后足下垂:未诊断出的糖尿病?

Postherpetic foot drop in an elderly case: undiagnosed diabetes mellitus?

作者信息

Öztürk Zeynep, Türkyılmaz Ayşe

机构信息

Department of Clinical Pharmacology and Toxicology, İzmir Atatürk Training and Research Hospital, İzmir, Turkey.

Department of Neurology, Atatürk Research Hospital, İzmir Atatürk Training and Research Hospital, İzmir, Turkey.

出版信息

Turk J Phys Med Rehabil. 2017 Jun 3;63(2):185-188. doi: 10.5606/tftrd.2017.34603. eCollection 2017 Jun.

Abstract

Postherpetic neuralgia is the most commonly seen complication of herpes zoster, primarily in elderly and immunocompromised patients. However, motor involvement due to herpes zoster is very rare. A 65-year-old male patient presented with left leg pain, numbness and difficulty walking. He was diagnosed with having herpes zoster and treated with valacyclovir. Despite anti-convulsant and physical therapy, the patient developed foot drop and had an unexplained weight loss. Clinical and laboratory findings suggested previously undiagnosed diabetes mellitus. Three weeks after initiation of insulin treatment, he became normoglycemic, his pain was reduced, and foot drop disappeared almost completely. Postherpetic motor involvement as an unusual complication may signal an underlying systemic disease, particularly in elderly.

摘要

带状疱疹后神经痛是带状疱疹最常见的并发症,主要见于老年人和免疫功能低下的患者。然而,带状疱疹引起的运动功能受累非常罕见。一名65岁男性患者出现左腿疼痛、麻木和行走困难。他被诊断为带状疱疹,并接受了伐昔洛韦治疗。尽管进行了抗惊厥治疗和物理治疗,但患者仍出现了足下垂,且体重莫名减轻。临床和实验室检查结果提示此前未被诊断出的糖尿病。开始胰岛素治疗三周后,他的血糖恢复正常,疼痛减轻,足下垂几乎完全消失。带状疱疹后运动功能受累作为一种不寻常的并发症可能预示着潜在的全身性疾病,尤其是在老年人中。

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Postherpetic foot drop in an elderly case: undiagnosed diabetes mellitus?老年患者的带状疱疹后足下垂:未诊断出的糖尿病?
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本文引用的文献

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Ageing as a risk factor for disease.衰老作为疾病的一个风险因素。
Curr Biol. 2012 Sep 11;22(17):R741-52. doi: 10.1016/j.cub.2012.07.024.
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Postherpetic neuralgia: the never-ending challenge.带状疱疹后神经痛:永无休止的挑战。
Pain Pract. 2005 Dec;5(4):327-40. doi: 10.1111/j.1533-2500.2005.00035.x.

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