Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Health Science Center, Xi'an Jiaotong University, Xi'an, China,
Am J Nephrol. 2019;50(4):240-254. doi: 10.1159/000502447. Epub 2019 Aug 27.
Inadequate dialysis, renal hypertension, and impaired exercise capacity are factors that affect the quality of life (QoL) and mortality of adults with end-stage renal disease (ESRD) undergoing hemodialysis (HD). This systematic review provided valid evidence about the effect of exercise training on single-pool Kt/V (sp Kt/V), blood pressure, and peak uptake oxygen (VO2 peak).
A systematic review and meta-analysis of published randomized controlled trials (RCTs) that evaluated the effects of no <8 weeks' exercise training on the physical fitness outcomes for adults with ESRD undergoing HD were accepted in this study.
Included 20 trials (677 participants) indicated that various exercise types improved aerobic capacity, walking capacity, and health-related QoL totally. Of note, aerobic exercise and combined exercise were the predominant exercise types.
Based on our evidence, aerobic exercise or combined exercise at least for 8 weeks to 12 months, 3 times weekly, will be beneficial to physical conditions of the patients with ESRD undergoing HD. The clinical staff can treat patients with the evidence above. Future studies need to provide more information basis for the construction of patient exercise system by adding various exercise combinations.
透析不充分、肾性高血压和运动能力受损是影响终末期肾病（ESRD）行血液透析（HD）患者生活质量（QoL）和死亡率的因素。本系统评价提供了关于运动训练对单池 Kt/V（sp Kt/V）、血压和峰值摄氧量（VO2 峰值）影响的有效证据。
本研究接受了对评估不超过 8 周运动训练对行 HD 的 ESRD 成人身体适应结果影响的已发表随机对照试验（RCT）的系统评价和荟萃分析。
包括 20 项试验（677 名参与者）表明，各种运动类型均可全面改善有氧能力、步行能力和与健康相关的 QoL。值得注意的是，有氧运动和综合运动是主要的运动类型。
根据我们的证据，至少进行 8 周至 12 个月、每周 3 次的有氧运动或综合运动对行 HD 的 ESRD 患者的身体状况有益。临床工作人员可以根据上述证据治疗患者。未来的研究需要通过增加各种运动组合来提供更多信息，为患者运动系统的构建提供依据。
