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2型糖尿病患者中与高血压相关的因素:来自资源有限地区——埃塞俄比亚南部的证据

Factors associated with hypertension among patients with type 2 diabetes: evidence from a resource-limited setting-Southern Ethiopia.

作者信息

Yakob Begidu, Israel Eskinder, Jaldo Mesfin Menza, Abraham Awoke, Yakob Tagese

机构信息

Montioring and Evaluation, Wolaita Zone Health Department, Wolaita Sodo, Ethiopia.

School of Public Health, College of Health Science and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.

出版信息

Front Endocrinol (Lausanne). 2025 Aug 1;16:1534852. doi: 10.3389/fendo.2025.1534852. eCollection 2025.

DOI:10.3389/fendo.2025.1534852
PMID:40822947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12353734/
Abstract

BACKGROUND

Globally, non-communicable diseases contribute to about three-quarters of all deaths. Developing nations face particular difficulties with the concurrent presence of diabetes and high blood pressure, problems intensified by poor nutrition habits, lack of physical exercise, and continuing high rates of illnesses like HIV/AIDS and malaria. A significant data gap in primary healthcare (PHC) data has been determined and prioritized by governments seeking to assess and enhance the prevention and management of chronic disease.

OBJECTIVE

The main aim of the current study is to determine factors related to hypertension among patients with type 2 diabetes in public PHC facilities in Southern Ethiopia.

METHODS

A facility-based cross-sectional study was conducted from 6 March 2023 to 5 April 2023 among 409 patients with diabetes. A systematic random sampling technique was employed to select the study participants. The data were cleaned, coded, and entered into Epi-data version 4.6.0.2 and exported to STATA version 14 for analysis. For descriptive statistics, both bivariate and multivariable logistic regression analyses were employed. Variables with a -value <0.05 in the multivariable logistic regression analysis were declared as significantly associated with outcome variables.

RESULTS

A total of 407 patients with type 2 diabetes mellitus (T2DM) were included in the current study with a response rate of 99.5%, and the mean age of the study participants was 57.1 years (SD ±9.91). The prevalence of hypertension among patients with T2DM was 66.1% with a 95% confidence interval (CI) of 59.9-70.3. The age group of >60 years [adjusted odds ratio (AOR) = 2.09, 95% CI (1.02-4.28)], patients with ≥10 years' duration of T2DM [AOR = 1.79, 95% CI (1.05-3.03)], body mass index ≥25 kg/m [AOR = 4.19, 95% CI (2.10-8.33)], and patients who have a family history of hypertension [AOR = 11.73, 95% CI (5.82-23.66)] were significantly associated with hypertension among patients with type 2 diabetes.

CONCLUSION

The prevalence of hypertension is high and the majority has poor blood pressure control. Hence, DM care providers and other health sector stakeholders have to work in collaboration to prevent it by designing appropriate strategies especially for those at higher risk of developing hypertension.

摘要

背景

在全球范围内,非传染性疾病约占所有死亡人数的四分之三。发展中国家在糖尿病和高血压并发方面面临特殊困难,不良的营养习惯、缺乏体育锻炼以及诸如艾滋病毒/艾滋病和疟疾等疾病的持续高发病率加剧了这些问题。各国政府在寻求评估和加强慢性病的预防与管理时,已确定并优先处理了初级卫生保健(PHC)数据方面的重大数据缺口。

目的

本研究的主要目的是确定埃塞俄比亚南部公共初级卫生保健机构中2型糖尿病患者高血压的相关因素。

方法

于2023年3月6日至2023年4月5日对409名糖尿病患者进行了一项基于机构的横断面研究。采用系统随机抽样技术选择研究参与者。数据进行了清理、编码,并录入Epi-data 4.6.0.2版本,然后导出到STATA 14版本进行分析。对于描述性统计,采用了双变量和多变量逻辑回归分析。多变量逻辑回归分析中P值<0.05的变量被宣布与结果变量显著相关。

结果

本研究共纳入407例2型糖尿病(T2DM)患者,应答率为99.5%,研究参与者的平均年龄为57.1岁(标准差±9.91)。T2DM患者中高血压患病率为66.1%,95%置信区间(CI)为59.9 - 70.3。年龄>60岁组[调整优势比(AOR)= 2.09,95% CI(1.02 - 4.28)]、T2DM病程≥10年的患者[AOR = 1.79,95% CI(1.05 - 3.03)]、体重指数≥25 kg/m²[AOR = 4.19,95% CI(2.10 - 8.33)]以及有高血压家族史的患者[AOR = 11.73,95% CI(5.82 - 23.66)]与2型糖尿病患者的高血压显著相关。

结论

高血压患病率高,且大多数患者血压控制不佳。因此,糖尿病护理提供者和其他卫生部门利益相关者必须合作,通过制定适当策略,特别是针对那些高血压发病风险较高的人群,来预防高血压。

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