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射频导管消融术所致胃轻瘫经枸橼酸莫沙必利治疗后成功缓解:两例病例报告。

Radiofrequency catheter ablation-induced gastroparesis successfully treated with administration of mosapride citrate: two case reports.

机构信息

Department of Gastroenterology, Aichi Medical University School of Medicine, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.

出版信息

Clin J Gastroenterol. 2020 Apr;13(2):182-185. doi: 10.1007/s12328-019-01038-x. Epub 2019 Aug 27.

DOI:10.1007/s12328-019-01038-x
PMID:31456172
Abstract

Atrial fibrillation (AF) is the most common cardiac arrhythmia, and radiofrequency catheter ablation (RFCA) for pulmonary vein isolation is a well-established therapeutic modality for AF. Transient gastroparesis rarely complicates RFCA. We report two cases of RFCA-induced transient gastroparesis, effectively treated with mosapride citrate administration. Case 1. Computed tomography (CT) performed 4 days after RFCA revealed marked gastric dilatation without any gastric or intestinal obstruction. The patient was fasting and was administered mosapride citrate (5 mg thrice a day). The patient's symptoms improved 6 days later, and CT revealed no gastric dilatation. Esophagogastroduodenoscopy revealed gastric peristalsis without residual food in the stomach. Case 2. CT performed 8 days after RFCA revealed marked gastric dilatation without any gastric or intestinal obstruction. The patient was fasting and was administered pantothenic acid (500 mg/day intravenously for 7 days). However, symptoms persisted, and CT revealed residual food in the stomach. The patient was subsequently administered mosapride citrate (5 mg thrice a day). The patient's symptoms improved 4 days later, and contrast-enhanced gastric X-ray using amidotrizoate meglumine revealed gastric peristalsis, passage of amidotrizoate meglumine into the duodenum, and no gastric dilatation. Mosapride citrate is useful to treat RFCA-induced gastroparesis.

摘要

心房颤动(AF)是最常见的心律失常,射频导管消融(RFCA)肺静脉隔离是 AF 的一种成熟的治疗方法。RFCA 很少引起短暂性胃轻瘫。我们报告了两例 RFCA 引起的短暂性胃轻瘫,给予枸橼酸莫沙必利治疗有效。病例 1. RFCA 后 4 天进行的计算机断层扫描(CT)显示胃明显扩张,但无胃或肠阻塞。患者禁食,并给予枸橼酸莫沙必利(每天 3 次,每次 5mg)。患者的症状在 6 天后改善,CT 显示胃无扩张。食管胃十二指肠镜检查显示胃蠕动,胃内无残留食物。病例 2. RFCA 后 8 天进行的 CT 显示胃明显扩张,但无胃或肠阻塞。患者禁食,并给予泛酸(每天 500mg 静脉注射 7 天)。然而,症状持续存在,CT 显示胃内有残留食物。随后给予枸橼酸莫沙必利(每天 3 次,每次 5mg)。患者的症状在 4 天后改善,用 amidotrizoate meglumine 进行增强胃 X 线检查显示胃蠕动,amidotrizoate meglumine 进入十二指肠,胃无扩张。枸橼酸莫沙必利对治疗 RFCA 引起的胃轻瘫有效。

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