Panzarasa Guido
Dipartimento di Scienze ed Innovazione Tecnologica, Università del Piemonte Orientale "Amedeo Avogadro", Alessandria 15100, Italy.
ACS Omega. 2018 Oct 15;3(10):13179-13182. doi: 10.1021/acsomega.8b02208. eCollection 2018 Oct 31.
Radziszewski amidation, namely the peroxide-mediated conversion of nitriles into amides, is a chemiluminescent reaction involving singlet oxygen. Its increasing relevance in green chemistry and analytical chemistry makes it an important subject to be discussed in advanced chemistry courses. To turn the attention of lecturers, teachers, and students toward this reaction, the history of its discovery as well as its practical applications is discussed. Moreover, a simple and effective experiment to demonstrate the chemiluminescent properties of Radziszewski amidation is provided.
拉齐谢夫斯基酰胺化反应，即过氧化物介导的腈转化为酰胺的反应，是一种涉及单线态氧的化学发光反应。它在绿色化学和分析化学中日益重要，使其成为高等化学课程中需要讨论的重要课题。为了引起讲师、教师和学生对该反应的关注，本文讨论了其发现历史及其实际应用。此外，还提供了一个简单有效的实验来证明拉齐谢夫斯基酰胺化反应的化学发光特性。
