Husain Nazik Elmalaika, Badie Suliman Ahmed Abdel, Abdelrahman Ismail, Bedri Shahinaz A, Musa Rasha M, Osman Hind E, Mustafa Ayda H, Gafer Nahla, Farah Ehab, Satir Ali Abdel, Ahmed Mohamed H, Osman Mugtaba, Khalil Atif A, Agaimy Abbas
Department of Pathology, Omdurman Islamic University, Sudan.
Department of Pathology, The National Ribat University, Sudan.
J Family Med Prim Care. 2019 Jul;8(7):2389-2394. doi: 10.4103/jfmpc.jfmpc_247_19.
Vitamin D deficiency is a worldwide concern. The aim of the current study was to determine the vitamin D level and its contributing factors in Sudanese women.
In this cross-sectional study, 251 Sudanese women attending Family Health Centers in Khartoum, Sudan were interviewed. Following the exclusion of confounding factors, samples from 190 women were analzsed. Serum 25 hydroxyvitamin D "25(OH) D" was quantified using competitive electrochemiluminescence immunoassay.
Participants' age ranged from 18 to 85 years with a mean age (±SD) of 40.2 (±14.06) years. The mean (±SD) vitamin D level was 13.4 (±6.72) ng/ml, ranged 3.00-36.5 ng/ml and the median was 12.7 ng/mL. In total, 157 out of 190 (82.6%) had vitamin D serum levels below 20 ng/ml (deficient); of whom, 52 (27.4%) were in the age group 21-30 years ( value = 0.228). The correlation between vitamin D level and residence outside Khartoum, sun-exposed face and hands, and face and limbs in comparison with being completely covered were found to be statistically significant ( values 0.008, 0.023, and 0.036).
This study displayed a high percentage (82.6%.) of vitamin D deficiency among women in Sudan, and this in part may indicate that sunshine alone cannot guarantee vitamin D sufficiency in the tropics. Family physicians in tropical countries should screen those with clinical presentations related to vitamin D deficiency.
维生素D缺乏是一个全球性问题。本研究旨在确定苏丹女性的维生素D水平及其影响因素。
在这项横断面研究中，对251名前往苏丹喀土穆家庭健康中心就诊的苏丹女性进行了访谈。排除混杂因素后，对190名女性的样本进行了分析。采用竞争性电化学发光免疫分析法对血清25羟维生素D“25(OH)D”进行定量分析。
参与者年龄在18至85岁之间，平均年龄（±标准差）为40.2（±14.06）岁。维生素D水平的平均值（±标准差）为13.4（±6.72）ng/ml，范围为3.00 - 36.5 ng/ml，中位数为12.7 ng/mL。在190名参与者中，共有157名（82.6%）的血清维生素D水平低于20 ng/ml（缺乏）；其中，52名（27.4%）在21 - 30岁年龄组（P值 = 0.228）。发现维生素D水平与喀土穆以外的居住地、面部和手部暴露于阳光下以及面部和四肢与完全遮盖相比之间的相关性具有统计学意义（P值分别为0.008、0.023和0.036）。
本研究显示苏丹女性中维生素D缺乏的比例很高（82.6%），这在一定程度上可能表明仅靠阳光照射并不能保证热带地区维生素D充足。热带国家的家庭医生应对有维生素D缺乏相关临床表现的患者进行筛查。
