Department of Urology, Osaka City University Graduate School of Medicine, Osaka, Osaka, Japan.
Department of Urology, Suita Municipal Hospital, Suita, Osaka, Japan.
Aging Male. 2020 Dec;23(5):1039-1045. doi: 10.1080/13685538.2019.1659767. Epub 2019 Aug 30.
To investigate the relationship between urodynamic study (UDS) data and recovery of urinary incontinence (UI) in elderly patients who underwent robot-assisted radical prostatectomy (RARP).
Seventy-five prostate cancer (PCa) patients received UDS before and at 3 months after RARP. They were divided into two groups; a younger group (<70 years old, = 47) and older group (≥70 years, = 28), and each was classified according to urinary continence (UC) or UI at 3 months post-RARP. Continence was defined as being pad-free or 1-safety pad usage per day.
In the older group, preoperative maximum urethral closure pressure (MUCP) in the UI group was significantly lower than that in the UC group. Detrusor overactivity (DO) rate was significantly higher in the older UI group than in the older UC group at both pre- and 3 months post-RARP. Persistent DO rate pre- and post-RARP was significantly higher in the older group than in the younger group. Regardless of age, postoperative DO was an independent predictor of UI 6 months post-RARP.
In elderly patients, low preoperative MUCP and both pre- and postoperative DO are associated with postoperative UI.
探讨接受机器人辅助根治性前列腺切除术(RARP)的老年患者尿动力学研究(UDS)数据与尿失禁(UI)恢复之间的关系。
75 例前列腺癌(PCa)患者在 RARP 前和 3 个月后接受 UDS。他们被分为两组;年轻组(<70 岁,n=47)和老年组(≥70 岁,n=28),每组根据 3 个月后 RARP 的尿控或 UI 进行分类。控尿定义为无尿垫或每天使用 1 个安全垫。
在老年组中,UI 组术前最大尿道闭合压(MUCP)明显低于 UC 组。术前和 RARP 后 3 个月,老年 UI 组的逼尿肌过度活动(DO)率明显高于老年 UC 组。术前和术后持续 DO 率在老年组明显高于年轻组。无论年龄大小,术后 DO 是术后 6 个月 UI 的独立预测因子。
在老年患者中,术前低 MUCP 和术前及术后 DO 与术后 UI 相关。