Krouskop T A, Brown H D, Gray K, Shively J, Romovacek G R, Spira M, Runyan R S
Baylor College of Medicine, Houston, Texas 77030.
Biomaterials. 1988 Sep;9(5):398-404. doi: 10.1016/0142-9612(88)90003-8.
Numerous percutaneous devices for power transmission and control to electrically powered, intracorporeal blood pumps have been used for periods ranging from 12 months to 4 yrs; however, consistent and reliable performance has not been achieved, due most frequently to the development of infection and sinus tracts at the percutaneous lead exit site. The present study showed that percutaneous devices fabricated from porous vitreous carbon can function satisfactorily in vivo over extended periods. The implant sites successfully resisted infection by normal flora bacteria for as long as 48 months, although superficial surface colonization and infection did occur after deliberate application of pathogens.
许多用于向体内电动血泵进行动力传输和控制的经皮装置已被使用，使用时间从12个月到4年不等；然而，尚未实现持续可靠的性能，最常见的原因是经皮导线出口部位出现感染和窦道。本研究表明，由多孔玻璃碳制成的经皮装置能够在体内长时间令人满意地发挥作用。植入部位成功抵御正常菌群细菌感染长达48个月，尽管在故意接种病原体后确实发生了表面定植和感染。
