Biedlingmaier J F, Samaranayake R, Whelan P
Division of Otolaryngology, University of Maryland Medical Center, Baltimore, USA.
Otolaryngol Head Neck Surg. 1998 Apr;118(4):444-51. doi: 10.1177/019459989811800403.
New materials and coatings are now being developed to resist permanent bacterial contamination of implanted medical devices. This study exposed several styles of middle ear ventilation tube materials and coatings to high concentrations of Pseudomonas and Staphylococcus. Electron microscopy was then used to evaluate these tubes' resistance to bacterial biofilm formations. Ionized, processed silicone tubes were the only tubes resistant to Pseudomonas adhesion. Tubes that were made of fluoroplastic or that were ionized processed were very resistant to Staphylococcus contamination when compared with untreated silicone or silver oxide-treated silicone. This study suggests that ionized, coated fluoroplastic would be a highly effective tube material in preventing bacterial biofilm contamination of implanted ventilation tubes.
目前正在研发新型材料和涂层，以抵抗植入式医疗器械的永久性细菌污染。本研究将几种中耳通气管材料和涂层暴露于高浓度的铜绿假单胞菌和葡萄球菌中。然后使用电子显微镜评估这些通气管对细菌生物膜形成的抗性。经过电离处理的硅胶管是唯一能抵抗铜绿假单胞菌粘附的管子。与未处理的硅胶管或经氧化银处理的硅胶管相比，由氟塑料制成或经过电离处理的管子对葡萄球菌污染具有很强的抗性。这项研究表明，经过电离处理的涂层氟塑料将是一种非常有效的管材，可防止植入式通气管受到细菌生物膜污染。
