Hughes S, Calverley P M
Intensive Therapy Unit, Walton Hospital, Liverpool.
BMJ. 1988 Dec 10;297(6662):1511-2. doi: 10.1136/bmj.297.6662.1511.
Opiate addiction is an increasing social problem, and there has been a change from taking opiates intravenously to inhaling them in many areas of Britain. Three patients with asthma who required mechanical ventilation soon after heroin inhalation were described. Two subsequently died of acute severe asthma. The patients were reluctant to admit to their addiction and persisted inhaling heroin despite medical advice and counselling. Opiate inhalation can provoke life threatening asthmatic attacks and should be considered in patients at risk of abusing drugs who have poorly controlled asthma.
阿片类药物成瘾是一个日益严重的社会问题，在英国许多地区，使用阿片类药物的方式已从静脉注射转变为吸入。本文描述了三名吸入海洛因后不久需要机械通气的哮喘患者。其中两名患者随后死于急性重症哮喘。这些患者不愿承认自己成瘾，尽管有医学建议和咨询，仍持续吸入海洛因。吸入阿片类药物可引发危及生命的哮喘发作，对于哮喘控制不佳且有药物滥用风险的患者应予以考虑。
