雾化阿片类药物在恶性疾病患者呼吸困难治疗中的临床应用。

Clinical application of nebulized opioids for treatment of dyspnoea in patients with malignant disease.

作者信息

Farncombe M, Chater S

机构信息

Palliative Care Service, Ottawa Civic Hospital, Ontario, Canada.

出版信息

Support Care Cancer. 1994 May;2(3):184-7. doi: 10.1007/BF00417478.

DOI:10.1007/BF00417478

PMID:7518312

Abstract

This article describes our experience in the clinical use of nebulized opioids for the management of dyspnoea in patients with terminal cancer by reviewing three specific patient case studies in which this treatment was found to be both safe and effective in controlling breathlessness. The patients were treated with morphine, hydromorphone or anileridine in various doses according to their prior use of opioids. Additional formal studies are being initiated at this Centre.

摘要

本文通过回顾三个具体病例研究描述了我们在临床中使用雾化阿片类药物治疗晚期癌症患者呼吸困难的经验，这些研究发现这种治疗在控制呼吸急促方面既安全又有效。根据患者之前使用阿片类药物的情况，给予不同剂量的吗啡、氢吗啡酮或阿尼利定进行治疗。该中心正在开展更多的正式研究。