Mills T J, Safford R E, Kazmier F J
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Int J Cardiol. 1988 Nov;21(2):190-4. doi: 10.1016/0167-5273(88)90224-0.
A 40-year-old man who presented with exertional angina had had two myocardial infarctions within the same myocardial distribution several years earlier. Coronary arteriography revealed a large intramural thrombus in the right coronary artery and minimal atherosclerotic disease. Special coagulation studies detected a circulating lupus anticoagulant. The association of repeated episodes of thrombosis and lupus anticoagulant is important. In patients with repeated thrombotic events, the lupus anticoagulant should be sought, particularly in those less than 40 years of age.
一名40岁男性因劳力性心绞痛就诊，数年前在同一心肌分布区域发生过两次心肌梗死。冠状动脉造影显示右冠状动脉有一个大的壁内血栓，动脉粥样硬化病变轻微。特殊凝血研究检测到循环狼疮抗凝物。反复血栓形成发作与狼疮抗凝物之间的关联很重要。在反复发生血栓事件的患者中，应寻找狼疮抗凝物，尤其是在40岁以下的患者中。
