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一名患有狼疮抗凝物的患者发生肝梗死。

Hepatic infarction in a patient with the lupus anticoagulant.

作者信息

Mor F, Beigel Y, Inbal A, Goren M, Wysenbeek A J

机构信息

Department of Internal Medicine B, Beilinson Medical Center, Petah Tiqva, Israel.

出版信息

Arthritis Rheum. 1989 Apr;32(4):491-5. doi: 10.1002/anr.1780320421.

DOI:10.1002/anr.1780320421
PMID:2495803
Abstract

We describe a 31-year-old patient with missed abortion, thrombocytopenia, and clinical, laboratory, and radiologic evidence of hepatic infarction. On evaluation, she was found to have the lupus anticoagulant. The association between enhanced thrombosis and the lupus anticoagulant is discussed, and previously reported thrombotic complications are described. The etiology, clinical course, and radiologic features of liver infarction are summarized, and the importance of recognizing and treating this form of hypercoagulability is stressed. To our knowledge, this is the first description of liver infarction associated with the lupus anticoagulant.

摘要

我们描述了一名31岁的稽留流产患者,伴有血小板减少症,并有肝脏梗死的临床、实验室及影像学证据。经评估,发现她患有狼疮抗凝物。本文讨论了血栓形成增强与狼疮抗凝物之间的关联,并描述了先前报道的血栓形成并发症。总结了肝梗死的病因、临床过程及影像学特征,并强调了认识和治疗这种高凝状态的重要性。据我们所知,这是首次对与狼疮抗凝物相关的肝梗死进行描述。

相似文献

1
Hepatic infarction in a patient with the lupus anticoagulant.一名患有狼疮抗凝物的患者发生肝梗死。
Arthritis Rheum. 1989 Apr;32(4):491-5. doi: 10.1002/anr.1780320421.
2
Association between lupus anticoagulant and epilepsy.狼疮抗凝物与癫痫之间的关联。
Ric Clin Lab. 1987 Jan-Mar;17(1):35-9. doi: 10.1007/BF02909386.
3
Lupus anticoagulant and lacunar infarctions.狼疮抗凝物与腔隙性脑梗死
Eur Neurol. 1988;28(3):174-6. doi: 10.1159/000116260.
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Skin lesions associated with circulating lupus anticoagulant.
Br J Dermatol. 1989 Mar;120(3):419-29. doi: 10.1111/j.1365-2133.1989.tb04170.x.
5
Lupus anticoagulant and cerebral infarction: therapeutic implications.
J Neurol. 1987 Jun;234(5):361-2. doi: 10.1007/BF00314297.
6
The use of warfarin in pregnancy complicated by circulating lupus anticoagulant; a technique for monitoring.华法林在合并循环狼疮抗凝物的妊娠期的应用;一种监测技术。
Eur J Obstet Gynecol Reprod Biol. 1988 Sep;29(1):27-32. doi: 10.1016/0028-2243(88)90161-x.
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Myocardial infarction, persistent coronary artery thrombosis and lupus anticoagulant.心肌梗死、持续性冠状动脉血栓形成与狼疮抗凝物
Int J Cardiol. 1988 Nov;21(2):190-4. doi: 10.1016/0167-5273(88)90224-0.
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Occlusion of small hepatic veins associated with systemic lupus erythematosus with the lupus anticoagulant and anti-cardiolipin antibody.与系统性红斑狼疮相关的小肝静脉闭塞,伴有狼疮抗凝物和抗心磷脂抗体。
Hepatogastroenterology. 1989 Oct;36(5):393-7.
9
Splenic infarction. A new thrombotic manifestation of the circulating lupus anticoagulant.脾梗死。循环中狼疮抗凝物的一种新的血栓形成表现。
Cleve Clin J Med. 1989 Mar-Apr;56(2):174-6. doi: 10.3949/ccjm.56.2.174.
10
Cerebral ischemic events associated with endocarditis, retinal vascular disease, and lupus anticoagulant.与心内膜炎、视网膜血管疾病和狼疮抗凝物相关的脑缺血事件。
Am J Med. 1991 Mar;90(3):299-309.

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Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome.
一名患有抗磷脂综合征且三联抗体阳性的孕妇发生肝梗死:一例聚焦于灾难性抗磷脂综合征的病例报告。
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Hepatic necrosis: a main presentation of systemic lupus erythematosus in a previously healthy woman.肝坏死:一名既往健康女性系统性红斑狼疮的主要表现。
Int J Prev Med. 2011 Oct;2(4):286-90.
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Unusual manifestations of the antiphospholipid syndrome.抗磷脂综合征的不寻常表现。
Clin Rev Allergy Immunol. 2003 Aug;25(1):61-78. doi: 10.1385/CRIAI:25:1:61.
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Gastrointestinal hemorrhage and intestinal ischemia associated with anticardiolipin antibodies.与抗心磷脂抗体相关的胃肠道出血和肠缺血
Dig Dis Sci. 1994 Jun;39(6):1359-64. doi: 10.1007/BF02093805.
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Subungual splinter haemorrhages: a new sign of the antiphospholipid coagulopathy?甲下线状出血:抗磷脂凝血障碍的新体征?
Ann Rheum Dis. 1990 Apr;49(4):268. doi: 10.1136/ard.49.4.268-a.
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Massive hepatic infarction in systemic lupus erythematosus.
Dig Dis Sci. 1990 Dec;35(12):1557-60. doi: 10.1007/BF01540576.
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The antiphospholipid syndrome: a syndrome in evolution.抗磷脂综合征:一种不断演变的综合征。
Ann Rheum Dis. 1992 Feb;51(2):147-50. doi: 10.1136/ard.51.2.147.