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经皮冠状动脉介入治疗相关的原发性和继发性血管入路部位并发症:来自 BMC2 注册研究的观察。

Primary and Secondary Vascular Access Site Complications Associated With Percutaneous Coronary Intervention: Insights From the BMC2 Registry.

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

Department of Cardiovascular Medicine, Beaumont Hospital, Royal Oak, Michigan.

出版信息

JACC Cardiovasc Interv. 2019 Nov 25;12(22):2247-2256. doi: 10.1016/j.jcin.2019.05.051. Epub 2019 Aug 28.

DOI:10.1016/j.jcin.2019.05.051
PMID:31473240
Abstract

OBJECTIVES

This study sought to describe the association between trends in primary and secondary vascular access sites and vascular access site complications (VASCs) among patients who underwent percutaneous coronary intervention (PCI) in Michigan.

BACKGROUND

The frequency of transradial PCI has increased. As a result, there is concern that operators may lose femoral-access proficiency resulting in a paradoxical increase in PCI complications. Anecdotally, an increase in secondary access use during PCI has also been observed.

METHODS

Data from the BMC2 (Blue Cross Blue Shield of Michigan Cardiovascular Consortium) registry was queried to evaluate the use of transradial and transfemoral PCI and their associated VASCs.

RESULTS

From 2013 to 2017, transradial PCI increased from 25.9% to 45.2% and the overall use of secondary vascular access increased from 4.9% to 8.7% with minimal change in overall VASCs (1.2% to 1.4%). The use of secondary vascular access was associated with increased VASCs (odds ratio [OR]: 5.82; 95% confidence interval [CI]: 5.26 to 6.43). Although, patients treated by operators in the highest tertile of radial use were more likely to experience femoral VASCs (adjusted OR: 1.51; 95% CI: 1.08 to 2.13), treatment by these operators was associated with an overall reduction in all VASCs (adjusted OR: 0.62; 95% CI: 0.46 to 0.83).

CONCLUSIONS

Despite increased use of transradial PCI, there has been no significant decrease in VASCs. This is in part attributable to an increased incidence of femoral VASCs and increasing use of secondary vascular access. An overall reduction in VASCs was observed in the highest radial use operators. Further strategies are needed to reduce VASCs in the transradial era.

摘要

目的

本研究旨在描述密歇根州经皮冠状动脉介入治疗(PCI)患者中主要和次要血管入路的趋势以及血管入路并发症(VASC)之间的关联。

背景

经桡动脉 PCI 的频率有所增加。因此,人们担心操作者可能会失去股动脉入路的熟练程度,导致 PCI 并发症出现反常增加。据推测,PCI 过程中也观察到了辅助血管入路使用的增加。

方法

从 BMC2(蓝十字蓝盾密歇根州心血管联合会)注册中心查询数据,以评估经桡动脉和经股动脉 PCI 的使用情况及其相关的 VASC。

结果

从 2013 年到 2017 年,经桡动脉 PCI 的比例从 25.9%增加到 45.2%,辅助血管入路的总体使用率从 4.9%增加到 8.7%,而总体 VASC 变化不大(从 1.2%增加到 1.4%)。辅助血管入路的使用与 VASC 的增加相关(比值比[OR]:5.82;95%置信区间[CI]:5.26 至 6.43)。尽管接受桡动脉使用率最高的操作者治疗的患者更有可能发生股动脉 VASC(校正 OR:1.51;95% CI:1.08 至 2.13),但这些操作者的治疗与所有 VASC 的总体减少相关(校正 OR:0.62;95% CI:0.46 至 0.83)。

结论

尽管经桡动脉 PCI 的使用率增加,但 VASC 并未显著降低。这部分归因于股动脉 VASC 的发生率增加和辅助血管入路使用的增加。在桡动脉使用率最高的操作者中观察到 VASC 的总体减少。在经桡动脉时代,需要进一步的策略来降低 VASC。

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