Manes Gianpiero, Andreozzi Paolo, Omazzi Barbara, Bezzio Cristina, Redaelli Davide, Devani Massimo, Morganti Daniela, Reati Raffaella, Saibeni Simone, Mandelli Enzo, Arena Ilaria, Hassan Cesare, de Nucci Germana
Department of Gastroenterology, ASST Rhodense, Rho and Garbagnate Milanese Hospital, Milan, Italy.
Gastroenterology Unit, ASL Caserta, Marcianise Hospital, Italy.
Endosc Int Open. 2019 Sep;7(9):E1135-E1142. doi: 10.1055/a-0854-3946. Epub 2019 Aug 29.
Withdrawal time (WT) monitoring and full-spectrum endoscopy (FUSE) have been suggested to increase adenoma detection rate (ADR) due to more accurate evaluation of the hidden areas of the colon. We aimed to evaluate the efficacy of WT monitoring and FUSE on ADR. This was a prospective observational study involving consecutive outpatients, aged 18 to 85 years, undergoing colonoscopy with unselected indications. In phase 1, endoscopists performed 660 colonoscopies either with standard forward-viewing endoscope (SFVE) (n = 330) or with FUSE (n = 330). In this phase, WTs were measured without endoscopist awareness of being monitored. In phase 2, endoscopists were informed of being monitored and performed additional 660 colonoscopies either with SFVE (n = 330) or with FUSE (n = 330). WT was lower in phase 1 compared to phase 2 (SFVE: 269 ± 83 vs. 386 ± 60 sec, < 0.001; FUSE: 289 ± 97 vs. 403 ± 65 sec, < 0.001). Use of FUSE increased ADR both in phase 1 (33.0 % vs. 27.3 %, = 0.127) and in phase 2 (41.8 % vs. 33.6 %, = 0.037). When endoscopists were aware of being monitored, ADR was higher in SFVE (33.6 % vs. 27.3 %; = 0.090) and FUSE arms (41.8 % vs. 33.0 %; = 0.024). Improvement in detection of proximal adenomas was associated with WT monitoring [OR 1.577 (95 % C. I. 1.158 - 2.148); = 0.004], whereas detection of distal adenomas was associated with use of FUSE [OR 1.320 (95 % C. I. 1.022 - 1.705); = 0.037]. Unmonitored endoscopists have suboptimal WT, which increases when they are monitored. WT monitoring and use of FUSE are two reliable and alternative strategies to increase ADR.
由于对结肠隐匿区域的评估更为准确,因此有人建议采用退镜时间(WT)监测和全谱内镜检查(FUSE)来提高腺瘤检出率(ADR)。我们旨在评估WT监测和FUSE对ADR的疗效。这是一项前瞻性观察性研究,纳入了年龄在18至85岁之间、因未选定的适应症而接受结肠镜检查的连续门诊患者。在第1阶段,内镜医师使用标准前视内镜(SFVE)(n = 330)或FUSE(n = 330)进行了660例结肠镜检查。在此阶段,测量退镜时间时内镜医师不知道自己正在被监测。在第2阶段,告知内镜医师他们正在被监测,然后他们使用SFVE(n = 330)或FUSE(n = 330)又进行了660例结肠镜检查。与第2阶段相比,第1阶段的WT更低(SFVE:269±83秒对386±60秒,P<0.001;FUSE:289±97秒对403±65秒,P<0.001)。在第1阶段(33.0%对27.3%,P = 0.127)和第2阶段(41.8%对33.6%,P = 0.037),使用FUSE均提高了ADR。当内镜医师知道自己正在被监测时,SFVE组(33.6%对27.3%;P = 0.090)和FUSE组(41.8%对33.0%;P = 0.024)的ADR更高。近端腺瘤检测的改善与WT监测相关[比值比(OR)1.5