Kaya Eda, Bakir Alev, Koseoglu Yusuf Kenan, Velidedeoglu Mehmet, Trabulus Sinan, Seyahi Nurhan
Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Fatih, Turkey.
Faculty of Medicine, Department of Biostatistics and Medical Informatics, Halic University, Istanbul, Turkey.
Prog Transplant. 2019 Dec;29(4):321-326. doi: 10.1177/1526924819873906. Epub 2019 Sep 2.
Phase angle is a bioimpedance analysis parameter that indirectly shows body cell mass. Its association with mortality has been shown in patients receiving dialysis treatment. However, assessment with mortality in kidney transplant recipients has not been studied previously.
We examined 158 kidney transplant recipients who underwent bioimpedance analysis 8 years ago in a cross-sectional study. We contacted them again and investigated the presence of cardiovascular events, cancer, angina pectoris, and claudication. Data regarding mortality, graft failure, and creatinine values were collected from recipients' files.
During the follow-up period, 15 recipients died, 26 lost graft function, 36 experienced cardiovascular events, and 4 developed cancer. Phase angle was significantly associated with mortality during the 8-year follow-up period of kidney transplant recipients ( < .001). The cutoff value for phase angle as a predictor of mortality was ≤5.85. Moreover, a phase angle value lower than 5.85 indicated 5.33 times higher risk of mortality.
Phase angle was a predictor of mortality in kidney transplant recipients. Since phase angle is an inexpensive, easy-to-perform, and noninvasive method, it might be considered as an additional tool to assess survival in kidney transplant recipients.
相位角是一种生物电阻抗分析参数，可间接反映身体细胞质量。其与死亡率的关联已在接受透析治疗的患者中得到证实。然而，此前尚未对肾移植受者的死亡率评估进行研究。
在一项横断面研究中，我们对158名8年前接受生物电阻抗分析的肾移植受者进行了检查。我们再次联系他们，调查心血管事件、癌症、心绞痛和跛行的发生情况。从受者档案中收集有关死亡率、移植物功能丧失和肌酐值的数据。
在随访期间，15名受者死亡，26名失去移植物功能，36名发生心血管事件，4名患癌症。在肾移植受者的8年随访期内，相位角与死亡率显著相关（<.001）。作为死亡率预测指标的相位角临界值为≤5.85。此外，相位角值低于5.85表明死亡风险高5.33倍。
相位角是肾移植受者死亡率的一个预测指标。由于相位角是一种廉价、易于实施且无创的方法，它可被视为评估肾移植受者生存情况的一种额外工具。
