Agroécologie, AgroSup Dijon, INRA, Université Bourgogne Franche-Comté Bourgogne, Université Bourgogne Franche-Comté, Dijon, France.
Génomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Université Evry, Université Paris-Saclay, Evry, France.
Nat Genet. 2019 Sep;51(9):1411-1422. doi: 10.1038/s41588-019-0480-1. Epub 2019 Sep 2.
We report the first annotated chromosome-level reference genome assembly for pea, Gregor Mendel's original genetic model. Phylogenetics and paleogenomics show genomic rearrangements across legumes and suggest a major role for repetitive elements in pea genome evolution. Compared to other sequenced Leguminosae genomes, the pea genome shows intense gene dynamics, most likely associated with genome size expansion when the Fabeae diverged from its sister tribes. During Pisum evolution, translocation and transposition differentially occurred across lineages. This reference sequence will accelerate our understanding of the molecular basis of agronomically important traits and support crop improvement.
我们报道了豌豆的第一个注释染色体水平参考基因组组装，豌豆是 Gregor Mendel 的原始遗传模型。系统发生学和古基因组学表明豆科植物的基因组重排，并表明重复元件在豌豆基因组进化中起主要作用。与其他已测序的豆科基因组相比，豌豆基因组显示出强烈的基因动态，这很可能与 Fabeae 从其姐妹部落分化时基因组大小的扩张有关。在豌豆属进化过程中，转座和转位在不同的谱系中发生。这个参考序列将加速我们对农艺重要性状的分子基础的理解，并支持作物改良。
