验证糖尿病药物依从性量表在黎巴嫩人群中的适用性。
Validation of diabetes medication adherence scale in the Lebanese population.
机构信息
Research Clinical Pharmacy and Pharmaco-epidemiology, Lebanon; Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Campus Hadath, Beirut, Lebanon.
Pharmacokinetics, Lebanon; Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Campus Hadath, Beirut, Lebanon.
出版信息
Diabetes Res Clin Pract. 2019 Oct;156:107837. doi: 10.1016/j.diabres.2019.107837. Epub 2019 Aug 31.
AIM
To validate the Diabetes Medication Adherence Scale (DMAS-7), determine its concordance with another validated scales and to assess factors affecting medication adherence.
METHODS
A cross-sectional study was conducted on a sample of Lebanese patients with diabetes using a questionnaire. The level of adherence was measured using the DMAS-7 and the Lebanese Medication Adherence Scale (LMAS-14). Bivariate and multivariate analyses were conducted, and the scale was validated in terms of reliability, predictive ability, and construct validity using SPSS version 19.
RESULTS
Out of 300 eligible patients, the rate of adherence was 33.7%. Measures of validity showed good reliability (Cronbach alpha = 0.627), and good construct validity with LMAS-14 (Spearman's rho = 0.846; Cohen's kappa = 0.711). DMAS-7 was found to be both correlated with LMAS-14 (ICC average measure = 0.675; p-value <0.001) in addition to possessing a better predictive value. Thus, DMAS-7 showed to have good concordance and increased validity compared to LMAS-14. Having an optimal glycated hemoglobin (HbA1C) (OR = 0.779; p = 0.001) and performing regular physical activity (OR 2.328; p = 0.002) increased medication adherence.
CONCLUSION
The DMAS-7 showed to be reliable and valid instrument superior to LMAS-14 in predicting adherence levels to oral anti-diabetic medications, and thus can be used to achieve better glycemic outcomes.
目的
验证糖尿病药物依从性量表（DMAS-7），确定其与另一个经过验证的量表的一致性，并评估影响药物依从性的因素。
方法
使用问卷对黎巴嫩的糖尿病患者进行了一项横断面研究。使用 DMAS-7 和黎巴嫩药物依从性量表（LMAS-14）来衡量依从性的水平。进行了单变量和多变量分析，并使用 SPSS 版本 19 评估了量表的可靠性、预测能力和结构有效性。
结果
在 300 名合格患者中，依从率为 33.7%。有效性测量显示出良好的可靠性（Cronbach alpha=0.627），与 LMAS-14 具有良好的结构有效性（Spearman's rho=0.846；Cohen's kappa=0.711）。DMAS-7 与 LMAS-14 相关（ICC 平均测量值=0.675；p 值<0.001），同时具有更好的预测价值。因此，DMAS-7 与 LMAS-14 相比具有良好的一致性和更高的有效性。糖化血红蛋白（HbA1C）达到最佳水平（OR=0.779；p=0.001）和定期进行体育锻炼（OR 2.328；p=0.002）可提高药物依从性。
结论
DMAS-7 是一种可靠且有效的工具，在预测口服抗糖尿病药物的依从性水平方面优于 LMAS-14，因此可用于实现更好的血糖控制效果。
Zotero 插件