DiGangi Brian A, Dingman Patricia A, Grijalva C Jaime, Belyeu Mark, Tucker Sylvia, Isaza Ramiro
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Box 100126, Gainesville, FL 32610, USA.
Maddie's Shelter Medicine Program, College of Veterinary Medicine, University of Florida, Box 100126, Gainesville, FL 32610, USA.
Vet Immunol Immunopathol. 2019 Dec;218:109933. doi: 10.1016/j.vetimm.2019.109933. Epub 2019 Aug 28.
The purpose of this study was to estimate the apparent prevalence and identify risk factors for antibody levels (AL) against canine distemper virus (CDV), canine parvovirus (CPV), and canine adenovirus (CAV) in three communities in the metropolitan area of Quito, Ecuador that have limited access to regular veterinary care. Whole blood samples were collected from 154 dogs presenting to three veterinary field clinics in mainland Ecuador and tested for AL against CDV, CPV, and CAV by a commercially available point-of-care ELISA. Potential risk factors for the presence of AL were analyzed. A majority of dogs had AL against CDV (66%, 95% CI = 58-73%), CPV (95%, 95% CI = 91-98%) and CAV (60%, 95% CI = 52-67%). Dogs had significantly greater odds of AL against CDV if they were >2 years of age, from an urban community, and had previously received veterinary care. Dogs had significantly greater odds of AL against CAV if they were male, >2 years of age, and had previously received veterinary care. Results provide baseline estimates of AL within each community and allow for the targeting of future veterinary services to communities and dogs most at risk.
本研究的目的是评估厄瓜多尔基多市大都市区三个社区中犬瘟热病毒（CDV）、犬细小病毒（CPV）和犬腺病毒（CAV）抗体水平（AL）的表观流行率，并确定相关风险因素，这些社区获得常规兽医护理的机会有限。从厄瓜多尔大陆的三家兽医现场诊所就诊的154只狗采集全血样本，通过市售的即时检测ELISA检测其针对CDV、CPV和CAV的AL。分析了AL存在的潜在风险因素。大多数狗对CDV（66%，95%CI = 58 - 73%）、CPV（95%，95%CI = 91 - 98%）和CAV（60%，95%CI = 52 - 67%）有AL。如果狗年龄大于2岁、来自城市社区且以前接受过兽医护理，则其对CDV有AL的几率显著更高。如果狗为雄性、年龄大于2岁且以前接受过兽医护理，则其对CAV有AL的几率显著更高。研究结果提供了每个社区内AL的基线估计，并有助于将未来的兽医服务目标对准风险最高的社区和狗。
